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Volume 27, Number 9—September 2021
Research

Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 to Close Contacts, China, January–February 2020

Yu Li1, Jianhua Liu1, Zhongcheng Yang1, Jianxing Yu, Chengzhong Xu, Aiqin Zhu, Hao Zhang, Xiaokun Yang, Xin Zhao, Minrui Ren, Zhili Li, Jinzhao Cui, Hongting Zhao, Xiang Ren, Chengxi Sun, Ying Cheng, Qiulan Chen, Zhaorui Chang, Junling Sun, Lance E. Rodewald, Liping Wang, Luzhao Feng, George F. Gao2, Zijian Feng2, and Zhongjie LiComments to Author 
Author affiliations: Chinese Center for Disease Control and Prevention, Beijing, China (Y. Li, J. Yu, A. Zhu, X. Yang, M. Ren, Zhili Li, J. Cui, H. Zhao, X. Ren, C. Sun, Y. Cheng, Q. Chen, Z. Chang, J. Sun, L.E. Rodewald, L. Wang, L. Feng, G.F. Gao, Z. Feng, Zhongjie Li); Yichang Center for Disease Control and Prevention, Yichang, China (J. Liu, Z. Yang, C. Xu, H. Zhang, X. Zhou)

Main Article

Table 3

Univariate and multivariate analyses of factors associated with secondary attack rate for coronavirus disease, China, January–February 2020*

Characteristic of contact Univariate
 Multivariate†
Crude OR (95% CI) p value Adjusted OR (95% CI) p value
Type of contact
Not living together Referent Referent
Living together
 7.85 (3.89–15.83)
 <0.01
5.12 (2.11–12.45)
 <0.01
Spouse of index case-patient
No Referent Referent
Yes
 6.46 (3.30–12.61)
 <0.01
2.83 (1.31–6.11)
 <0.01
Age of contact, y
<60 Referent Referent
≥60
 3.29 (1.86–5.82)
 <0.01
2.61 (1.43–4.78)
 0.01
Age of index case-patient, y
<60 Referent Referent
≥60
 5.13 (1.66–15.86)
 <0.01
2.92 (0.80–10.59)
 0.1
Most recent contact with index case-patient
Before illness Referent Referent
After illness 2.20 (1.06–4.59) 0.03 1.23 (0.49–3.07) 0.66

*Multilevel logistic regression model of mixed effects accounted for random effects of index cases. OR, odds ratio. †Other covariates included in the model were contact type, whether the contact was a spouse of the index case-patient, age of contact, age of index case-patient, and most recent contact with index case-patient.

Main Article

1These authors contributed equally to this article.

2These authors are the senior authors.

Page created: June 21, 2021
Page updated: August 17, 2021
Page reviewed: August 17, 2021
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