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Volume 28, Number 11—November 2022

Deaths Related to Chagas Disease and COVID-19 Co-Infection, Brazil, March–December 2020

Francisco R. Martins-MeloComments to Author , Marcia C. Castro, Antonio Luiz P. Ribeiro, Jorg Heukelbach, and Guilherme L. Werneck
Author affiliations: Federal Institute of Education, Science, and Technology of Ceará, Fortaleza, Brazil (F.R. Martins-Melo); Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA (M.C. Castro); Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (A.L.P. Ribeiro); Federal University of Ceará, Fortaleza (J. Heukelbach); Federal University of Rio de Janeiro, Rio de Janeiro, Brazil (G.L. Werneck); State University of Rio de Janeiro, Rio de Janeiro (G.L. Werneck)

Main Article

Table 1

Underlying causes on death certificates that listed Chagas disease and COVID-19 co-infection, Brazil, March–December 2020*

Underlying causes of death (ICD-10 codes) No. (%)
Coronavirus disease 19 – COVID-19 (B34.2, U07.1, U07.2)† 434 (88.2)
Coronavirus infection, unspecified site + COVID-19, virus identified (laboratory confirmed) (B34.2 + U07.1) 335 (68.1)
Coronavirus infection, unspecified site + COVID-19, virus not identified (clinically or epidemiologically diagnosed (B34.2 + U07.2) 52 (10.6)
Coronavirus infection, unspecified site (B34.2) 47 (9.6)
Chagas disease (B57, K23.1, K93.1) 38 (7.7)
Chagas disease (chronic) with heart involvement (B57.2) 27 (5.5)
Chagas disease (chronic) with digestive system involvement (B57.3) 6 (1.2)
Acute Chagas disease with heart involvement (B57.0) 3 (0.6)
Chagas disease (chronic) with nervous system involvement (B57.4) 2 (0.4)
Pneumonia (J12-J18) 3 (0.6)
Chronic obstructive pulmonary disease (J40-J44) 3 (0.6)
Diabetes mellitus (E10-E14) 2 (0.4)
Hypertensive diseases (I10-I15) 2 (0.4)
Other respiratory disorders (J98) 1 (0.2)
Infection due to other mycobacteria (A31) 1 (0.2)
Sepsis (A40-A41) 1 (0.2)
Secondary and unspecified malignant neoplasm of lymph nodes (C77) 1 (0.2)
Dementia (F00-F04) 1 (0.2)
Other disorders of brain (G93) 1 (0.2)
Appendicitis (K35-K37) 1 (0.2)
Paralytic ileus and intestinal obstruction without hernia (K56) 1 (0.2)
Cholelithiasis (K80) 1 (0.2)
Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and puerperium (O98) 1 (0.2)
Total 492 (100.0)

*COVID-19, coronavirus disease; ICD-10, International Statistical Classification of Diseases and Related Health Problems, 10th revision. †ICD-10 codes were based on the Brazilian Ministry of Health codification guidelines for COVID-19 (, which recommends the standardized use of the ICD-10 code B34.2 (Coronavirus infection, unspecified site) for deaths of COVID-19 in Brazil, with the inclusion of pandemic marker codes U07.1 (COVID-19, identified virus) or U07.2 (COVID-19, unidentified virus, clinical or epidemiologic criteria), defined by the World Health Organization, next to code B34.2 in the same line of the death certificate.

Main Article

Page created: September 14, 2022
Page updated: October 24, 2022
Page reviewed: October 24, 2022
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