Volume 28, Number 5—May 2022
CME ACTIVITY - Synopsis
Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018–2019
Laura E. Nabarro, Colin S. Brown, Sooria Balasegaram, Valérie Decraene, James Elston, Smita Kapadia, Pauline Harrington, Peter Hoffman, Rachel Mearkle, Bharat Patel, Derren Ready, Esther Robinson, and Theresa Lamagni
Table 2
Summary of home healthcare–associated invasive group A Streptococcus infection outbreaks, England, 2018–2019*
| Outbreak no. | No. iGAS cases | No. GAS cases† | No. deaths | No. days from first to last case | No. cases without identified HHC input | emm type | WGS |
|---|---|---|---|---|---|---|---|
| 1 | 14 | 2 | 2 | 136 | 1 | 87 | N |
| 2 | 7 | 1 | 2 | 148 | 0 | 94 | N |
| 3 | 6 | 0 | 3 | 222 | 0 | 94 | Y |
| 4 | 7 | 0 | 2 | 388 | 0 | 89 | Y |
| 5 | 5 | 5 | 2 | 179 | 2 | 89 | N |
| 6 | 3 | 0 | 0 | 75 | 0 | 1 | Y |
| 7 | 4 | 0 | 0 | 219 | 0 | 1 | Y |
| 8 | 2 | 0 | 1 | 3 | 0 | 89 | Y |
| 9 | 9 | 1 | 1 | 507 | 0 | 89 | Y |
| 10 |
39 |
95 |
15 |
487 |
1 |
44 |
Y |
| Total | 96 | 104 | 28 | NA | 4 | NA | NA |
*GAS, group A Streptococcus; HHC, home healthcare; iGAS, invasive group A Streptococcus; NA, not applicable; WGS, whole-genome sequencing. †Noninvasive GAS was not systematically investigated or recorded in all outbreaks. Available data did not enable distinction between carriage and noninvasive infection.
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