Duration of Infectious Virus Shedding by SARS-CoV-2 Omicron Variant–Infected Vaccinees
, Masahiro Ishikane1
, Mugen Ujiie, Noriko Iwamoto, Nobumasa Okumura, Testsuro Sato, Maki Nagashima, Ataru Moriya, Michiyo Suzuki, Masayuki Hojo, Takayuki Kanno, Shinji Saito, Sho Miyamoto, Akira Ainai, Minoru Tobiume, Takeshi Arashiro, Tsuguto Fujimoto, Tomoya Saito, Masaya Yamato, Tadaki Suzuki
, and Norio Ohmagari
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (K. Takahashi, T. Kanno, S. Saito, S. Miyamoto, A. Ainai, M. Tobiume, T. Arashiro, T. Fujimoto, T. Saito, T. Suzuki); National Center for Global Health and Medicine, Tokyo (M. Ishikane, M. Ujiie, N. Iwamoto, N. Okumura, T. Sato, M. Nagashima, A. Moriya, M. Suzuki, M. Hojo, N. Ohmagari); Rinku General Medical Center, Osaka, Japan (M. Yamato)
Figure 2. SARS-CoV-2 RNA level and infectious virus shedding in upper respiratory samples from symptomatic patients infected with the SARS-CoV-2 Omicron variant, Japan, November 29–December 18, 2021. A) SARS-CoV-2 RNA levels and presence of the infectious virus, by date of symptom onset. Each closed circle indicates case-patients from whom virus was isolated. Numbers above each plot indicate the proportion of case-patients from whom virus was isolated in each period. Black lines indicate median Cq values and error bars interquartile ranges; dotted lines indicate negative cutoff values. *Before symptom onset. B) SARS-CoV-2 RNA levels and presence of infectious virus, by date of symptom resolution. Closed circles indicate patients from whom virus was isolated. Numbers above each plot indicate the proportion of persons from whom virus was isolated in each period. Black lines indicate median Cq values and error bars interquartile ranges; dotted lines indicate cutoff values. †Before symptom resolution. Cq, quantification cycle; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
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