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Volume 28, Number 6—June 2022
Research Letter

Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination

Rune M. Pedersen, Line L. Bang, Lone W. Madsen, Thomas V. Sydenham, Isik S. Johansen, Thøger G. Jensen, Ulrik S. Justesen, and Thomas E. AndersenComments to Author 
Author affiliation: Authors affiliation: University of Southern Denmark, Odense, Denmark

Main Article

Figure

Results of PRNT90 of serum against SARS-CoV-2 ancestral strain and Omicron sublineages BA.1 and BA.2 after BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) booster vaccination, Denmark. Serum samples were collected from 20 SARS-CoV-2–naive participants who received 2 BNT162b2 doses and a booster BNT162b2 dose. Viral genome sequences are available in GenBank (accession nos. ON055855 for the ancestral strain, ON055874 for BA.1, and ON055857 for BA.2). Red line indicates neutralization threshold; black lines indicate median neutralization titers for each strain. PRNT90, 90% plaque reduction neutralization test.

Figure. Results of PRNT90 of serum against SARS-CoV-2 ancestral strain and Omicron sublineages BA.1 and BA.2 after BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) booster vaccination, Denmark. Serum samples were collected from 20 SARS-CoV-2–naive participants who received 2 BNT162b2 doses and a booster BNT162b2 dose. Viral genome sequences are available in GenBank (accession nos. ON055855 for the ancestral strain, ON055874 for BA.1, and ON055857 for BA.2). Red line indicates neutralization threshold; black lines indicate median neutralization titers for each strain. PRNT90, 90% plaque reduction neutralization test.

Main Article

Page created: March 30, 2022
Page updated: May 22, 2022
Page reviewed: May 22, 2022
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