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Volume 28, Number 7—July 2022

Highly Pathogenic Avian Influenza A(H5N8) Clade Virus in Dust Samples from Poultry Farms, France, 2021

Fabien Filaire, Laetitia Lebre, Charlotte Foret-Lucas, Timothée Vergne, Patrick Daniel, Aurélie Lelièvre, Antoine de Barros, Adam Jbenyeni, Pierrick Bolon, Mathilde Paul, Guillaume Croville, and Jean-Luc Guérin
Author affiliations: THESEO France, Laval, France (F. Filaire); Université de Toulouse, Toulouse, France (F. Filaire, L. Lebre, C. Foret-Lucas, T. Vergne, A. De Barros, A. Jbenyeni, P. Bolon, M. Paul, G. Croville, J.-L. Guérin); Laboratoires des Pyrénées et des Landes, Mont-de-Marsan, France (P. Daniel); SOCSA 40, Amou, France (A. Lelièvre)

Main Article

Table 1

Estimated sensitivity of sampling methods and sampling strategies by latent class analysis for detection of highly pathogenic avian influenza A(H5N8) virus on poultry farms, France, December 2020–April 2021

Clinical signs Samples* Estimated sensitivity of sampling method (95% credible interval)† Estimated sensitivity of sampling strategy (95% credible interval)‡
Clinical signs in flock Tracheal swab 0.77 (0.44–0.99) 1.00 (0.90–1.00)
Wipe 0.89 (0.64–1.00) 0.99 (0.87–1.00)
Coriolis 0.93 (0.69–1.00) 0.93 (0.69–1.00)

0.93 (0.69–1.00)
0.93 (0.69–1.00)
No clinical signs in flock Tracheal swab 0.46 (0.15–0.97) 0.92 (0.48–1.00)
Wipe 0.90 (0.67–1.00) 0.99 (0.89–1.00)
Coriolis 0.92 (0.63–1.00) 0.92 (0.63–1.00)
NIOSH BC 251 0.67 (0.34–0.91) 0.67(0.34–0.91)

*Each farm or building was sampled by using 20 tracheal swab samples (pooled in sets of 5 for RT-PCR) and 2 wipe samples from surfaces; on 19 farms we also collected 1 air sample from each of the 2 aerosol collection devices, the Coriolis Compact (Bertin Instruments, and the NIOSH BC 251 developed by the National Institute for Occupational Safety and Health ( †Sampling method relates to the simple analysis of individual samples; individual tracheal swab samples are those analyzed in pools of 5 samples; thus, the sensitivity of the sampling method corresponds to the probability that a single sample, or a pooled sample for the tracheal swabs, tests positive in an infected poultry house. ‡Sampling strategy relates to the combined analysis of the different individual samples at the farm or building level, assuming that the farm or building is positive when >1 individual sample tests positive; thus, the sensitivity of the sampling strategy corresponds to the probability that >1 sample, or >1 pool of 5 tracheal swab samples, tests positive in an infected poultry house.

Main Article

Page created: May 03, 2022
Page updated: June 18, 2022
Page reviewed: June 18, 2022
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