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Volume 28, Number 7—July 2022
Research

Self-Reported and Physiologic Reactions to Third BNT162b2 mRNA COVID-19 (Booster) Vaccine Dose

Merav Mofaz, Matan Yechezkel, Grace Guan, Margaret L. Brandeau, Tal Patalon, Sivan Gazit, Dan Yamin1, and Erez Shmueli1Comments to Author 
Author affiliations: Tel Aviv University, Tel Aviv, Israel (M. Mofaz, M. Yechezkel, D. Yamin, E. Shmueli); Stanford University, Stanford, California, USA (G. Guan, M.L. Brandeau); Maccabi Healthcare Services, Tel Aviv (T. Patalon, S. Gazit); Massachusetts Institute of Technology Media Laboratory, Cambridge Massachusetts, USA (E. Shmueli)

Main Article

Figure 3

Changes in objective physiologic indicators measured through smartwatch for self-reported and physiologic reactions to BNT162b2 (Pfizer, https://www.pfizer.com) mRNA coronavirus disease vaccine doses. Mean difference are shown for smartwatch-recorded heart rate (A‒C), HRV-based stress (D‒F), and SpO2 (G‒I) after the first, second, and third dose compared with their baseline levels. Mean values are indicated by solid lines; 90% CIs are indicated as shaded regions. Horizontal dashed line indicates no change compared with baseline levels, and vertical lines indicate 24-hour periods. HRV, heart-related variability; SpO2, blood oxygen saturation level.

Figure 3. Changes in objective physiologic indicators measured through smartwatch for self-reported and physiologic reactions to BNT162b2 (Pfizer, https://www.pfizer.com) mRNA coronavirus disease vaccine doses. Mean difference are shown for smartwatch-recorded heart rate (A‒C), HRV-based stress (D‒F), and SpO2 (G‒I) after the first, second, and third dose compared with their baseline levels. Mean values are indicated by solid lines; 90% CIs are indicated as shaded regions. Horizontal dashed line indicates no change compared with baseline levels, and vertical lines indicate 24-hour periods. HRV, heart-related variability; SpO2, blood oxygen saturation level.

Main Article

1These authors contributed equally to this article.

Page created: April 12, 2022
Page updated: June 18, 2022
Page reviewed: June 18, 2022
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