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Volume 28, Number 8—August 2022
Research

Factors Associated with Delayed or Missed Second-Dose mRNA COVID-19 Vaccination among Persons >12 Years of Age, United States

Lu Meng, Neil Chandra Murthy, Bhavini Patel Murthy, Elizabeth Zell, Ryan Saelee, Megan Irving, Hannah E. Fast, Patricia Castro Roman, Adam Schiller, Lauren Shaw, Carla L. Black, Lynn Gibbs-Scharf, LaTreace Harris, and Terence ChorbaComments to Author 
Author affiliations: Centers for Disease Control and Prevention Atlanta, Georgia, USA (L. Meng, N.C. Murthy, B.P. Murthy, E. Zell, R. Saelee, M. Irving, H.E. Fast, P.Castro Roman, A. Schiller, L. Shaw, C.L. Black, L. Gibbs-Scharf, L. Harris, T. Chorba); General Dynamics Information Technology Inc., Falls Church, Virginia, USA (L. Meng, R. Saelee); Stat-Epi Associates, Inc., Ponte Vedra Beach, Florida, USA (E. Zell); Deloitte Consulting LLP, New York, New York, USA (M. Irving); Booz Allen Hamilton, Inc., McLean, Virginia, USA (A. Schiller)

Main Article

Table 2

Logistic regression models examining sociodemographic factors associated with delayed or missed second dose of a 2-dose primary mRNA COVID-19 vaccine series, United States, December 14, 2020–December 31, 2021*

Variable
 Model 1
Model 2
Delayed second dose,† n = 141,204,219
 Missed second dose,‡ n = 155,847,451
Coefficient estimate
 OR (95% CI)
 Coefficient estimate
 OR (95% CI)
Vaccine type, dose 1
Moderna 0.237 1.267 (1.265–1.270)§ −0.012 0.988 (0.987–0.989)
Pfizer-BioNTech
 Referent
Referent
Age group,y
12–17 −0.271      0.763 (0.759–(0.766)§ −0.064 0.938 (0.936–0.940)
40–64 −0.112 0.894 (0.892–0.896) −0.301 0.740 (0.739–0.741)§
>65 −0.008 0.992 (0.990–0.995) −0.298 0.743 (0.741–0.744)§
18–39
 Referent
Referent
Sex
F 0.006 1.006 (1.004–1.008) −0.082 0.922 (0.921–0.923)
M
 Referent
Referent
Urbanicity
Metro 0.048 1.049 (1.046–1.052) −0.038 0.963 (0.961–0.965)
Nonmetro
 Referent
Referent
Social Vulnerability Index (12)
High 0.181 1.198 (1.196–1.201)§ 0.155 1.168 (1.166–1.170)§
Medium 0.092 1.096 (1.094–1.099) 0.260 1.297 (1.295–1.299)§
Low
 Referent
Referent
Race/ethnicity
Hispanic 0.159 1.172 (1.168–1.175)§ 0.560 1.751 (1.748–1.754)§
Black 0.270 1.310 (1.305–1.314)§ 0.320 1.377 (1.373–1.380)§
American Indian/Alaska Native 0.411 1.508 (1.494–1.522)§ 1.015 2.760 (2.746–2.774)§
Asian/OPI 0.010 1.010 (1.005–1.015 0.128 1.137 (1.134–1.140)
Other/unknown 0.117 1.124 (1.122–1.127) 0.397 1.487 (1.485–1.489)§
White
 Referent
Referent
Region
South 0.354 1.425 (1.421–1.429)§ 0.277 1.319 (1.317–1.322)§
Midwest −0.007 0.993 (0.990–0.996) −0.246 0.782 (0.780–0.783) §
Mountain 0.499 1.648 (1.641–1.655)§ 0.070 1.072 (1.069–1.075)
Pacific 0.410 1.507 (1.503–1.512)§ 0.448 1.566 (1.563–1.568)§
Noncontiguous 0.634 1.886 (1.863–1.909)§ 1.111 3.038 (3.020–3.056)§
Northeast Referent Referent

*Pfizer-BioNTech, https://www.pfizer.com; Moderna, https://www.modernatx.com. OPI, Other Pacific Islander; OR, odds ratio. †Second dose administered >42 d after first dose. This model examins factors associated with a delayed second dose, conditional on receiving a second dose. ‡Received the first dose but no matching second dose on record. §Factors with OR >1.150 or <0.850.

Main Article

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Page created: June 22, 2022
Page updated: July 20, 2022
Page reviewed: July 20, 2022
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