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Volume 28, Number 9—September 2022

Age-Dependent Effects of COVID-19 Vaccine and of Healthcare Burden on COVID-19 Deaths, Tokyo, Japan

Yura K. KoComments to Author , Hiroaki Murayama, Lisa Yamasaki, Ryo Kinoshita, Motoi Suzuki, and Hiroshi Nishiura
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (Y.K. Ko, R. Kinoshita, M. Suzuki); Tohoku University, Miyagi, Japan (Y.K.Ko); International University of Health and Welfare, Chiba, Japan (H. Murayama); University of Tokyo, Tokyo (L. Yamasaki); Nagasaki University, Nagasaki, Japan (L. Yamasaki); Kyoto University, Kyoto, Japan (H. Nishiura)

Main Article


Estimated COVID-19 vaccine effectiveness in terms of protection against death over test-positive and unconditional protection against death, by age group, Tokyo, Japan, January 1–August 31, 2021*

Effect of interest, by age, y Vaccine effectiveness (95% credible interval)
Partially vaccinated* Fully vaccinated†
Protection against death over documented infection
30–59 y 34.2 (2.2–71.4) 38.0 (2.6–82.4)
60–69 y 66.1 (33.0–85.4) 88.6 (64.3–98.1)
70–79 y 38.2 (7.3–63.8) 83.9 (68.8–92.9)
80–89 y 46.4 (17.9–68.7) 83.5 (72.5–91.0)
>90 y
52.7 (19.6–76.6)
77.7 (60.7–89.4)
Unconditional protection against death
30–59 y 68.7 (53.5–86.4) 93.8 (90.3–98.2)
60–69 y 83.9 (68.1–93.0) 99.2 (97.4–99.9)
70–79y 70.6 (55.9–82.8) 99.3 (98.6–99.7)
80–89 y 74.5 (60.9–85.1) 99.4 (98.9–99.6)
>90 y 77.5 (61.8–88.8) 98.4 (97.1–99.2)

*14 d after the first vaccination and <14 d after the second vaccination. †14 d after the second vaccination.

Main Article

Page created: July 12, 2022
Page updated: August 19, 2022
Page reviewed: August 19, 2022
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