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Volume 29, Number 1—January 2023

Online Report

Efficiency of Field Laboratories for Ebola Virus Disease Outbreak during Chronic Insecurity, Eastern Democratic Republic of the Congo, 2018–2020

Daniel Mukadi-BamulekaComments to Author , Fabrice Mambu-Mbika, Anja De Weggheleire, François Edidi-Atani, Junior Bulabula-Penge, Meris Matondo Kua Mfumu, Anaïs Legand, Antoine Nkuba-Ndaye, Yannick Tutu Tshia N’kasar, Placide Mbala-Kingebeni, John D. Klena, Joel M. Montgomery, Jean-Jacques Muyembe-Tamfum, Pierre Formenty, Johan van Griensven, Kevin K. Ariën, and Steve Ahuka-Mundeke
Author affiliations: Rodolphe Merieux INRB-Goma Laboratory, Goma, Democratic Republic of the Congo (D. Mukadi-Bamuleka); Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo (D. Mukadi-Bamuleka, F. Mambu-Mbika, F. Edidi-Atani, J. Bulabula-Penge, M. Matondo Kua Mfumu, A. Nkuba-Ndaye, P. Mbala-Kingebeni, J.-J. Muyembe-Tamfum, S. Ahuka-Mundeke); University of Kinshasa, Kinshasha (D. Mukadi-Bamuleka, F. Mambu-Mbika, F. Edidi-Atani, J. Bulabula-Penge, M. Matondo Kua Mfumu, A. Nkuba-Ndaye, P. Mbala-Kingebeni, J.-J. Muyembe-Tamfum, S. Ahuka-Mundeke); Institute of Tropical Medicine, Antwerp, Belgium (A. De Weggheleire, J. van Griensven, K.K. Ariën); World Health Organization, Geneva, Switzerland (A. Legand, P. Formenty); Direction de la Surveillance Epidémiologique, Kinshasa (Y. Tutu Tshia N’kasar); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.D. Klena, J.M. Montgomery); University of Antwerp, Antwerp, Belgium (K.K. Ariën)

Main Article

Table 1

Type of setup, activities, and sites in field laboratories for EVD outbreak, eastern Democratic Republic of the Congo, 2018–2020*

Type of laboratory setup Activities performed Sites/provinces
Basic
 EVD diagnosis: GeneXpert (+)†; Chemistry: Piccolo (+/–)‡
 Tchomia/Ituri, Bunia/Ituri, Tchowe/South-Kivu
Bukavu/South-Kivu, Biakato/Ituri, Kasindi/North-Kivu
Standard§
 EVD diagnosis: GeneXpert (+); Chemistry: Piccolo (+); Hematology: pocH-100i (+)¶; Ebola survivors clinic
 Mangina/North-Kivu, Goma/North-Kivu, Komanda/Ituri, Mambasa/Ituri
Advanced§ EVD diagnosis: GeneXpert (+); Chemistry: Piccolo (+); Hematology: pocH-100i; Ebola survivors clinic; EVD differential diagnosis (Smart cycler or RPA) (+)
    or genomic sequencing (+)		 Beni/North-Kivu, Butembo/North-Kivu, Katwa/North-Kivu

*EVD, Ebola virus disease; RPA, recombinase polymerase amplification. †GeneXpert, (Cepheid, https://www.cepheid.com). ‡Abaxis (https://www.abaxis.com). §Sysmex (https://www.sysmex.com). ¶Research support: Ebola therapeutics through a Monitored Emergency Use of Unregistered and Investigational Interventions (MEURI) protocol or the Pamoja Tulinde Maisha/Together save lives (PALM) randomized controlled trial; the immunogenicity of rVSV-ZEBOV-GP vaccine; and the study of Ebola virus reservoir in bats.

Main Article

Page created: November 30, 2022
Page updated: December 22, 2022
Page reviewed: December 22, 2022
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