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Volume 29, Number 12—December 2023
Dispatch

Divergent Genotype of Hepatitis A Virus in Alpacas, Bolivia, 2019

Talitha Veith, L. Fabian Beltran-Saavedra, Tobias Bleicker, Marie Luisa Schmidt, José L. Mollericona, Kim Grützmacher, Rob Wallace, Jan Felix Drexler, Christian Walzer, Terry C. Jones, Christian Drosten, and Victor Max CormanComments to Author 
Author affiliations: Charité-Universitätsmedizin Berlin—corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany (T. Veith, T. Bleicker, M.L. Schmidt, J.F. Drexler, T.C. Jones, C. Drosten, V.M. Corman); Wildlife Conservation Society, La Paz, Bolivia (L.F. Beltran-Saavedra, J.L. Mollericona, R. Wallace); Wildlife Conservation Society, New York, New York, USA (L.F. Beltran-Saavedra, J.L. Mollericona, R. Wallace, C. Walzer); Museum für Naturkunde Berlin/Leibniz-Institute for Evolution and Biodiversity Science, Berlin (K. Grützmacher); Deutsche Gesellschaft für Internationale Zusammenarbeit GmbH, Bonn, Germany (K. Grützmacher); German Centre for Infection Research (DZIF), Berlin (J.F. Drexler, C. Drosten, V.M. Corman); University of Veterinary Medicine Vienna, Vienna, Austria (C. Walzer); University of Cambridge, Cambridge, UK (T.C. Jones); Labor Berlin Charité–Vivantes GmbH, Berlin (V.M. Corman)

Main Article

Table 1

Nucleotide distance matrix of complete HAV genomes in alpacas, Bolivia, 2019*

Genome Ucha-alp-14 Chu-alp-21 IA IB IIA IIB IIIA IIIB V
Chu-alp-21 7.6
IA 18.6 19
IB 18.6 19.1 8.7
IIA 19.5 20.1 14.2 14.2
IIB 18.7 19.2 14.1 14.2 9.2
IIIA 18.2 18.6 17.3 17.3 17.3 17.2
IIIB 18.1 18.8 17 17 17.4 17.3 10.8
V 20.8 21 19.1 19 19.5 19 19.5 19.3
VI 21.4 22 20.5 20.8 21 21 20.3 19.9 20.3

*Alpaca HAV and existing Hepatovirus A genotypes were included where complete genomes were available. Bold indicates intra-genotype distances. Genomes were aligned using ClustalOmega 1.2 (http://www.clustal.org/omega) in Geneious Prime 2023.1.2 (https://www.geneious.com). Nucleotide distances, given in percentages, were calculated in Geneious Prime 2023.1.2. Accession numbers used: IA, AB020564; IB, M14707; IIA, AY644670; IIB, AY644676; IIIA, AB279732; IIIB, AB279735; V, EU140838; VI, OQ559662. HAV, hepatitis A virus.

Main Article

Page created: September 05, 2023
Page updated: November 18, 2023
Page reviewed: November 18, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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