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Volume 29, Number 3—March 2023
Research Letter

Babesia microti Causing Intravascular Hemolysis in Immunocompetent Child, China

Jiafeng Yao1, Guoging Liu1, Yang Zou, Jin Jiang, Shaogang Li, Heng Wang, Xiaoling Cheng, Rui Zhang, Kaige Zhang, Chunyan WeiComments to Author , and Runhui WuComments to Author 
Author affiliations: Beijing Children’s Hospital, Beijing, China (J. Yao, G. Liu, J. Jiang, X. Cheng, R. Zhang, K. Zhang, R. Wu); Capital Medical University, Beijing (Y. Zou, S. Li); Peking Union Medical College School of Basic Medicine, Beijing (H. Wang, C. Wei)

Main Article

Table

Laboratory test results for Babesia microti causing intravascular hemolysis in immunocompetent child, China*

Variable Age-adjusted reference value or range Value
Epstein-Barr virus
Negative
Negative
Mycoplasma pneumoniae Negative Positive
IgM titer <1:80 1:80
Drug-resistance gene
Negative
Negative
Leukocyte count, × 109 cells/L 4.9–12.7 4.36
Erythrocyte count, × 1012 cells/L 4.1–5.5 2
Hemoglobin, g/L 115–150 57
Mean corpuscular volume, μm3 76–88 83
Mean corpuscular hemoglobin concentration, g/L 309–359 343
Platelet count, × 109/L 187–475 100
% Reticulocytes 0.5%–2.5% 2.07%
Clotting function
NA
Normal
Bilirubin, μmol/L
Total 3.42–20.5 55.98
Direct 0–3.42 13.76
Indirect
0–17.1
42.22
Aspartate aminotransferase, U/L 14–44 196.2
Alanine aminotransferase, U/L 7–30 187.6
Lactate dehydrogenase, U/L
110–295
2,899
Antiglobulin tests
IgG Negative Negative
C3d Negative Negative
DAT Negative Negative
Control
Negative
negative
Spot urine sample
Urine color Light yellow Brown
Ketone body Negative 1+
Protein Negative 2+
Urinary bilirubin
Negative
1+
Occult blood Negative 3+
Centrifugal microscopy for erythrocytes, HPF 0–3 0
Centrifugal microscopy for leukocytes, HPF
0–3
0
Chest computed tomography
NA
Few shadows in lower lobe of right lung, no exudative lesion
Abdominal ultrasound NA Splenomegaly

*DAT, direct antiglobulin test; HPF, high-power field; NA, not applicable.

Main Article

1These authors contributed equally to this article.

Page created: December 27, 2022
Page updated: February 21, 2023
Page reviewed: February 21, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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