Volume 29, Number 3—March 2023
Research Letter
Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
Table
Patient data from study of intrahost viral genome variation from 4 patients with early monkeypox virus infection, Finland, 2022*
Data |
Patient no. |
|||
---|---|---|---|---|
1 |
2 |
3 |
4 |
|
Age, y |
30s |
20s |
30s |
30s |
Onset of symptoms |
May 19 |
May 21 |
Jun 1 |
Jun 13 |
Systemic signs/symptoms |
Fever, enlarged inguinal lymph nodes |
Fever, headache, exhaustion, enlarged inguinal lymph nodes |
Fever, myalgia, lymphadenopathy, nausea, myalgia |
Fever, headache, anal itch |
Lesion sites |
Penis |
Penis, neck, trunk, face |
Trunk, hands, feet, anus |
Perianal skin |
Evolution of lesions |
Synchronous |
Asynchronous |
Asynchronous |
Synchronous |
Swab sample lesion sites (Cq value) |
Penis (19.77) |
Face (26.29), trunk (31.94) |
Hand (33.38) |
Perianal skin (23.4) |
Monkeypox virus sequence† |
ON782021‡ |
ON782022 (face) |
NA |
ON959143 |
Sample date | May 24, D5 | May 31, D10 | Jun 5, D4 | Jun 16, D3 |
*All 4 patients were men who have sex with men who had recent sexual exposure and who had traveled to southern Europe. Cq value, quantitative cycle value of diagnostic orthopoxvirus PCR (Appendix); D, day after first symptom onset; NA, not available. †GenBank accession numbers. ‡Majority sequence.