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Volume 29, Number 3—March 2023
Dispatch

Reemergence of Lymphocytic Choriomeningitis Mammarenavirus, Germany

Calvin Mehl, Claudia Wylezich, Christina Geiger, Nicole Schauerte, Kerstin Mätz-Rensing, Anne Nesseler, Dirk Höper, Miriam Linnenbrink, Martin Beer, Gerald Heckel, and Rainer G. UlrichComments to Author 
Author affiliations: Friedrich-Loeffler-Institut, Greifswald–Insel Riems, Germany (C. Mehl, C. Wylezich, D. Höper, M. Beer, R.G. Ulrich); German Center for Infection Research, Hamburg–Lübeck–Borstel–Riems, Germany (C. Mehl, R.G. Ulrich); Zoo Frankfurt, Frankfurt, Germany (C. Geiger, N. Schauerte); German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany (K. Mätz-Rensing); Landeslabor Hessen, Giessen, Germany (A. Nesseler); Max Planck Institute for Evolutionary Biology, Plön, Germany (M. Linnenbrink); University of Bern, Institute of Ecology and Evolution, Bern, Switzerland (G. Heckel)

Main Article

Figure

Phylogeny of the L protein encoding nucleotide sequences of lymphocytic choriomeningitis virus (LCMV) identified in Germany (blue arrows) and reference sequences, constructed by using Bayesian inference. Lunk virus from Mus minutoides mice was used as an outgroup. Sequence names are comprised of the GenBank accession number, strain name, host species and country of origin (wherever known). Countries are represented by their International Organization for Standardization code (AU, Australia; BG, Bulgaria; CN, China; DE, Germany; ES, Spain; FR, France; GA, Gabon; GF, French Guiana; JP, Japan; SK, Slovakia; US, USA; YU, former Yugoslavia). Roman numerals (I–IV) represent the different LCMV lineages defined according to Albariño et al. (2); WE and Armstrong refer to laboratory strains of LCMV. Mm, Mus musculus; Mmm, Mus musculus musculus; Mmd, Mus musculus domesticus.

Figure. Phylogeny of the L protein encoding nucleotide sequences of lymphocytic choriomeningitis virus (LCMV) identified in Germany (blue arrows) and reference sequences, constructed by using Bayesian inference. Lunk virus from Mus minutoides mice was used as an outgroup. Sequence names are comprised of the GenBank accession number, strain name, host species and country of origin (wherever known). Countries are represented by their International Organization for Standardization code (AU, Australia; BG, Bulgaria; CN, China; DE, Germany; ES, Spain; FR, France; GA, Gabon; GF, French Guiana; JP, Japan; SK, Slovakia; US, USA; YU, former Yugoslavia). Roman numerals (I–IV) represent the different LCMV lineages defined according to Albariño et al. (2); WE and Armstrong refer to laboratory strains of LCMV. Mm, Mus musculus; Mmm, Mus musculus musculus; Mmd, Mus musculus domesticus.

Main Article

References
  1. Meyer  BJ. Arenaviruses: Genomic RNAs, transcription, and replication. In: Oldstone MBA, editor. Arenaviruses I. Berlin: Springer; 2002. p. 139–57.
  2. Albariño  CG, Palacios  G, Khristova  ML, Erickson  BR, Carroll  SA, Comer  JA, et al. High diversity and ancient common ancestry of lymphocytic choriomeningitis virus. Emerg Infect Dis. 2010;16:1093100. DOIPubMedGoogle Scholar
  3. Armstrong  C, Lillie  RD. Experimental lymphocytic choriomeningitis of monkeys and mice produced by a virus encountered in studies of the 1933 St. Louis encephalitis epidemic. Public Health Reports (1896–1970). 1934;49(35):1019–27.
  4. Goldwater  PN. A mouse zoonotic virus (LCMV): A possible candidate in the causation of SIDS. Med Hypotheses. 2021;158:110735. DOIPubMedGoogle Scholar
  5. Ledesma  J, Fedele  CG, Carro  F, Lledó  L, Sánchez-Seco  MP, Tenorio  A, et al. Independent lineage of lymphocytic choriomeningitis virus in wood mice (Apodemus sylvaticus), Spain. Emerg Infect Dis. 2009;15:167780. DOIPubMedGoogle Scholar
  6. Ackermann  R, Stille  W, Blumenthal  W, Helm  EB, Keller  K, Baldus  O. [Syrian hamsters as vectors of lymphocytic choriomeningitis] [in German]. Dtsch Med Wochenschr. 1972;97:172531. DOIPubMedGoogle Scholar
  7. Ackermann  R, Körver  G, Turss  R, Wönne  R, Hochgesand  P. [Prenatal infection with the virus of lymphocytic choriomeningitis: report of two cases (author’s transl)] [in German]. Dtsch Med Wochenschr. 1974;99:62932. DOIPubMedGoogle Scholar
  8. Asper  M, Hofmann  P, Osmann  C, Funk  J, Metzger  C, Bruns  M, et al. First outbreak of callitrichid hepatitis in Germany: genetic characterization of the causative lymphocytic choriomeningitis virus strains. Virology. 2001;284:20313. DOIPubMedGoogle Scholar
  9. Ackermann  R, Stammler  A, Armbruster  B. Isolation of the lymphocytic choriomeningitis virus from curettage material after contact of the pregnant woman with a Syrian gold hamster (Mesocricetus auratus) [in German]. Infection. 1975;3:479. DOIGoogle Scholar
  10. Enders  G, Varho-Göbel  M, Löhler  J, Terletskaia-Ladwig  E, Eggers  M. Congenital lymphocytic choriomeningitis virus infection: an underdiagnosed disease. Pediatr Infect Dis J. 1999;18:6525. DOIPubMedGoogle Scholar
  11. Ackermann  R, Bloedhorn  H, Küpper  B, Winkens  I, Scheid  W. [Spread of the lymphocytic choriomeningitis virus among West German mice. I. Investigations mostly on domestic mice (Mus musculus)] [in German]. Zentralbl Bakteriol Orig. 1964;194:40730.PubMedGoogle Scholar
  12. Fornůsková  A, Hiadlovská  Z, Macholán  M, Piálek  J, de Bellocq  JG. New perspective on the geographic distribution and evolution of lymphocytic choriomeningitis virus, central Europe. Emerg Infect Dis. 2021;27:263847. DOIPubMedGoogle Scholar
  13. Wasimuddin  BJ, Bryja  J, Ribas  A, Baird  SJ, Piálek  J, Goüy de Bellocq  J. Testing parasite ‘intimacy’: the whipworm Trichuris muris in the European house mouse hybrid zone. Ecol Evol. 2016;6:2688701. DOIPubMedGoogle Scholar
  14. Vieth  S, Drosten  C, Lenz  O, Vincent  M, Omilabu  S, Hass  M, et al. RT-PCR assay for detection of Lassa virus and related Old World arenaviruses targeting the L gene. Trans R Soc Trop Med Hyg. 2007;101:125364. DOIPubMedGoogle Scholar
  15. Ronquist  F, Teslenko  M, van der Mark  P, Ayres  DL, Darling  A, Höhna  S, et al. MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space. Syst Biol. 2012;61:53942. DOIPubMedGoogle Scholar

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