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Volume 29, Number 5—May 2023
Dispatch

Novel Circovirus in Blood from Intravenous Drug Users, Yunnan, China

Yanpeng Li, Peng Zhang, Mei Ye, Ren-Rong Tian, Na Li, Le Cao, Yingying Ma, Feng-Liang Liu, Yong-Tang ZhengComments to Author , and Chiyu ZhangComments to Author 
Author affiliations: Fudan University, Shanghai, China (Y. Li, P. Zhang, L. Cao, Y. Ma, C. Zhang); Chinese Academy of Sciences, Kunming, China (M. Ye, R.-R. Tian, N. Li, F.-L. Liu, Y.-T. Zheng); Kunming Medical University, Kunming (N. Li)

Main Article

Figure 1

Genomic features of HuCV2 and its phylogenetic relationship with other circoviruses. A) Typical circular genome organization of HuCV2. B) Phylogenetic tree, generated based on the full-length genomic sequences, highlights HuCV2 from 2 patients in China (red circle and red diamond), another circovirus detected in humans (in addition to HuCV1), and the most widely studied known pathogens (PCV1–4). The phylogenetic tree was built in MEGA X (https://www.megasoftware.net) by using the neighbor-joining method. Bootstrap analysis with 1,000 replicates was applied to assess the phylogeny. Scale bar indicates number of nucleotide substitutions per site. Cap, capsid protein; HuCV, human-associated circovirus; ORF3, open reading frame 3; PCV, porcine circovirus; rep, replication-associated protein.

Figure 1. Genomic features of HuCV2 and its phylogenetic relationship with other circoviruses. A) Typical circular genome organization of HuCV2. B) Phylogenetic tree, generated based on the full-length genomic sequences, highlights HuCV2 from 2 patients in China (red circle and red diamond), another circovirus detected in humans (in addition to HuCV1), and the most widely studied known pathogens (PCV1–4). The phylogenetic tree was built in MEGA X (https://www.megasoftware.net) by using the neighbor-joining method. Bootstrap analysis with 1,000 replicates was applied to assess the phylogeny. Scale bar indicates number of nucleotide substitutions per site. Cap, capsid protein; HuCV, human-associated circovirus; ORF3, open reading frame 3; PCV, porcine circovirus; rep, replication-associated protein.

Main Article

Page created: February 24, 2023
Page updated: April 19, 2023
Page reviewed: April 19, 2023
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