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Volume 29, Number 7—July 2023
Dispatch

Fatal Invasive Mold Infections after Transplantation of Organs Recovered from Drowned Donors, United States, 2011–2021

Karen WuComments to Author , Pallavi Annambhotla, Rebecca J. Free, Jana M. Ritter, Brooke Leitgeb, Brendan R. Jackson, Mitsuru Toda, Sridhar V. Basavaraju, and Jeremy A.W. Gold
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure

Invasive fungal infection in transplanted liver from an organ donor who drowned, United States (case 2). A) Centrilobular hepatic necrosis without substantial inflammation; fungal hyphae are in a central vein (arrow) and throughout the sinusoids. Hematoxylin–eosin; original magnification ×100. B) Numerous fungal hyphae are in the lumen and wall of a large hepatic vessel. Hematoxylin–eosin; original magnification ×200. C) Grocott methenamine silver stain highlights ribbon-like, pauciseptate, branching funal hyphae within the hepatic vessel. Original magnification ×200. D) Intravascular fungal hyphae stain red by immunohistochemical assay for mucormycete fungi. Original magnification ×200.

Figure. Invasive fungal infection in transplanted liver from an organ donor who drowned, United States (case 2). A) Centrilobular hepatic necrosis without substantial inflammation; fungal hyphae are in a central vein (arrow) and throughout the sinusoids. Hematoxylin–eosin; original magnification ×100. B) Numerous fungal hyphae are in the lumen and wall of a large hepatic vessel. Hematoxylin–eosin; original magnification ×200. C) Grocott methenamine silver stain highlights ribbon-like, pauciseptate, branching funal hyphae within the hepatic vessel. Original magnification ×200. D) Intravascular fungal hyphae stain red by immunohistochemical assay for mucormycete fungi. Original magnification ×200.

Main Article

Page created: May 31, 2023
Page updated: June 20, 2023
Page reviewed: June 20, 2023
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