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Volume 29, Number 8—August 2023
Research Letter

Imported Cholera Cases, South Africa, 2023

Anthony M. SmithComments to Author , Phuti Sekwadi, Linda K. Erasmus, Christine C. Lee, Steven G. Stroika, Sinenhlanhla Ndzabandzaba, Vinitha Alex, Jeremy Nel, Elisabeth Njamkepo, Juno Thomas, and François-Xavier Weill
Author affiliations: University of Pretoria, Pretoria, South Africa (A.M. Smith); National Institute for Communicable Diseases, Johannesburg, South Africa (A.M. Smith, P. Sekwadi, L.K. Erasmus, J. Thomas); US Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.C. Lee, S.G. Stroika); National Heath Laboratory Service, Johannesburg (S. Ndzabandzaba, V. Alex); University of the Witwatersrand, Johannesburg (S. Ndzabandzaba, V. Alex, J. Nel); Institut Pasteur, Université Paris Cité, Paris, France (E. Njamkepo, F.-X. Weill)

Main Article

Figure

Maximum-likelihood phylogeny of Vibrio cholerae O1 El Tor isolates collected in South Africa, 2023, compared with 1,443 reference seventh pandemic V. cholerae El Tor (7PET) genomic sequences. A6 was used as the outgroup. The genomic waves and acquisition of the ctxB7 allele are indicated. Color coding indicates the geographic origins of the isolates; sublineages previously introduced into Africa (AFR1, AFR3–AFR14) are shown at right. A magnification of the clade containing the 6 isolates from South Africa (red text) is shown at right. For each genome, name (or accession number), country where contamination occurred, and year of sample collection are shown at the tips of the tree. The 6 isolates collected in South Africa belong to a new 7PET wave 3 sublineage called AFR15. Blue dots indicate bootstrap values ≥90%. Scale bars indicate number of nucleotide substitutions per variable site.

Figure. Maximum-likelihood phylogeny of Vibrio cholerae O1 El Tor isolates collected in South Africa, 2023, compared with 1,443 reference seventh pandemic V. cholerae El Tor (7PET) genomic sequences. A6 was used as the outgroup. The genomic waves and acquisition of the ctxB7 allele are indicated. Color coding indicates the geographic origins of the isolates; sublineages previously introduced into Africa (AFR1, AFR3–AFR14) are shown at right. A magnification of the clade containing the 6 isolates from South Africa (red text) is shown at right. For each genome, name (or accession number), country where contamination occurred, and year of sample collection are shown at the tips of the tree. The 6 isolates collected in South Africa belong to a new 7PET wave 3 sublineage called AFR15. Blue dots indicate bootstrap values ≥90%. Scale bars indicate number of nucleotide substitutions per variable site.

Main Article

Page created: June 15, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
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