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Volume 3, Number 2—June 1997
THEME ISSUE
From the 1st International Conference on Emerging Zoonoses
From the 1st International Conference on Emerging Zoonoses

The Hantaviruses of Europe: from the Bedside to the Bench

Jan Clement*, Paul Heyman*, Paula McKenna*, Paul Colson†, and Tatjana Avsic-Zupanc‡
Author affiliations: *Queen Astrid Military Hospital, Brussels, Belgium; †Centre de Santé des Fagnes, Chimay, Belgium; and ‡University of Ljubljana, Ljubljana, Slovenia

Main Article

Figure

Dendrogram of Old World hantaviruses (upper, left, and lower part of the tree) vs. New World hantaviruses (right part of the tree). Reproduced with permission (42). Branch lengths are proportional to genetic distances. The bootstrap support percentages of particular branching points calculated from 500 replicates are given in ovals. HTN = Hantaan virus, strain 76-118; SEO = Seoul virus, strain SR-11; DOB = Dobrava virus, PH = Prospect Hill virus; TUL = Tula virus, strains Tula/76Ma/87, Moravia/5

Figure. Dendrogram of Old World hantaviruses (upper, left, and lower part of the tree) vs. New World hantaviruses (right part of the tree). Reproduced with permission (42). Branch lengths are proportional to genetic distances. The bootstrap support percentages of particular branching points calculated from 500 replicates are given in ovals. HTN = Hantaan virus, strain 76-118; SEO = Seoul virus, strain SR-11; DOB = Dobrava virus, PH = Prospect Hill virus; TUL = Tula virus, strains Tula/76Ma/87, Moravia/5286Ma/94 and Malacky/Ma32/94; ILV = Isla Vista virus, strain MC-SB-1; TOP = Topografov virus; PUU = Puumala virus, strains Sotkamo, Vindeln/83-L20 and Udmurtia/458g/88; RIOS = Rio Segundo virus, strain RMx-Costa-1; ELMC = El Moro Canyon virus, strain RM-97; BAY = Bayou virus, strain Louisiana; BCC = Black Creek Canal virus; SN = Sin Nombre virus, strain H10; NY = New York virus, strain RI-1; KBR = Khabarovsk virus, another PUU-like virus, is not depicted here. PH & ILV (and BLL, not depicted here) are the only New World genotypes with PUU-like characteristics, hence their position close to the TUL-clade.

Main Article

References
  1. Myhrman  G. A renal disease with particular symptoms. Nordisk Medicinsk Tidskrift. 1934;7:793–4.
  2. Stuhlfauth  K. Bericht über ein neues schlammfieberähnliches Krankheitsbild bei Deutscher Truppen in Lappland. Dtsch Med Wochenschr. 1943;439:474–7. DOIGoogle Scholar
  3. Mustonen  J, Vaheri  A, Clement  J. Congress report: Third International Conference on Haemorrhagic Fever with Renal Syndrome (HFRS) and Hantaviruses. Nephrol Dial Transplant. 1996;11:730–3.PubMedGoogle Scholar
  4. Le Guenno  B, Coudrier  D. Epidemiology of hantavirus infections in France (1977-1995). Proceedings of the Third International Conference on HFRS and Hantaviruses 1994 May 31-June 3; Helsinki, Finland. Helsinki: Haartman Institute, University of Helsinki, 1994;11.
  5. Clement  J, Underwood  P, Ward  D, Pilaski  J, LeDuc  J. Hantavirus outbreak during military manoeuvres in Germany. Lancet. 1996;347:336. DOIPubMedGoogle Scholar
  6. Papadimitriou  MG, Antoniadis  A. Hantavirus nephropathy in Greece. Lancet. 1994;343:1038. DOIPubMedGoogle Scholar
  7. Gerding  M, Groen  J, Jordans  JGM, Osterhaus  ADME. Hantavirus nephropathy in the Netherlands: clinical, histopathological and epidemiological findings. Neth J Med. 1995;47:106–12. DOIPubMedGoogle Scholar
  8. Vapalahti  O, Vaheri  A, Henttonen  H. Eurosurveillance. Commission of the European Communities, Brussels, Belgium; 1995 Sept. European Communicable Disease Bulletin, No.0:3-4.
  9. Niklasson  B, LeDuc  J. Epidemiology of nephropathia epidemica in Sweden. J Infect Dis. 1987;155:269–76.PubMedGoogle Scholar
  10. Zöller  L, Faulde  M, Meisel  H, Ruh  B, Kimmig  P, Schelling  U, Seroprevalence of hantavirus antibodies in Germany as determined by a new recombinant enzyme immunoassay. Eur J Clin Microbiol Infect Dis. 1995;14:305–13. DOIPubMedGoogle Scholar
  11. Groen  J, Gerding  MN, Jordans  JG, Clement  JP, Nieuwenhuijs  JH, Osterhaus  AD. Hantavirus infections in The Netherlands: epidemiology and disease. Epidemiol Infect. 1995;114:373–83. DOIPubMedGoogle Scholar
  12. Clement  J, van der Groen  G. Acute Hantavirus nephropathy in Belgium: preliminary results of a sero-epidemiological study. In: Amerio A, Coratelli B, editors. Acute Renal Failure. Advances in experimental medicine and biology. New York: Plenum Press, 1987:251-63.
  13. Rodriguez  JA, Vaque  J. Hantavirus disease: an emerging infection [editorial]. Enferm Infecc Microbiol Clin. 1994;12:477–9.PubMedGoogle Scholar
  14. Niklasson  B, Leduc  JW, Nystrom  K, Nyman  L. Nephropathia epidemica: incidence of clinical cases and antibody prevalence in an endemic area of Sweden. Epidemiol Infect. 1987;99:559–62. DOIPubMedGoogle Scholar
  15. Colson  P, Damoiseaux  P, Brisbois  J, Duvvier  E, Levecque  P, Roger  JM, Hantavirose dans l'Entre-Sambre-et-Meuse. Acta Clin Belg. 1995;50:197–206.PubMedGoogle Scholar
  16. Clement  J, Colson  P, McKenna  P. Hantavirus pulmonary syndrome in New England and Europe. N Engl J Med. 1994;331:545–6. DOIPubMedGoogle Scholar
  17. Stuart  LM, Rice  PS, Lloyd  G, Beale  RJ. A soldier in respiratory distress. Lancet. 1996;347:30. DOIPubMedGoogle Scholar
  18. World Health Organization Working Group on the development of a rapid diagnostic method and vaccine for hemorrhagic fever with renal syndrome. Seoul, Republic of Korea, 1991 Sep 26-28; WPR/OCD/CDS(O)/1/91/IB3.
  19. Haemorrhagic fever with renal syndrome. Wkly Epidemiol Rec. 1993;68:189–91.PubMedGoogle Scholar
  20. Groen  J, Jordans  H, Clement  J, Rooijakkers  E, Uytdehaag  F, Dalrymple  J, Identification of hantavirus serotypes by testing of post-infection sera in immunofluorescence and enzyme-linked immunosorbent assays. J Med Virol. 1991;33:26–32. DOIPubMedGoogle Scholar
  21. Alexeyev  O, Elgh  F, Zhestkov  A, Wadell  G, Juto  P. Hantaan and Puumala virus antibodies in blood donors in Samara, an HFRS-endemic region in European Russia. Lancet. 1996;347:1483. DOIGoogle Scholar
  22. LeDuc  JW, Smith  GA, Childs  JE, Pinheiro  FP, Maiztegui  JI, Niklasson  B, Global survey of anti-body to hantaan related viruses among peridomestic rodents. Bull World Health Organ. 1986;64:139–44.PubMedGoogle Scholar
  23. Monteiro  J, Mesquita  M, Alves  MJ, Filipi  AR. Febre Hemorragica com Sindroma Renal - Primeiro caso clinico diagnosticado em Portugal. Separata da Revista Portuguesa de Doenas Infecciosas. 1993;16:209–14.
  24. Filipe  AR, Andrade  HR, Sommer  AI, Traavik  T. Hantaviral antigens and antibodies in wild rodents in Portugal. Acta Virol. 1991;35:287–91.PubMedGoogle Scholar
  25. McKenna  P, Clement  J, Matthys  P, Coyle  PV, McCaughey  C. Serological evidence of hantavirus disease in Northern Ireland. J Med Virol. 1994;43:33–8. DOIPubMedGoogle Scholar
  26. McCaughey  C, Montgomery  WI, Twomey  N, Addley  M, O'Neill  HJ, Coyle  PV. Evidence of hantavirus in wild rodents in Northern Ireland. Epidemiol Infect. 1996;117:361–5. DOIPubMedGoogle Scholar
  27. Dzagurova  T, Myasnikov  Y, Dekonenko  A, Tkachenko  E. Seoul-type hantavirus isolated from HFRS patient in European Russia. Proceedings of the Third International Conference on HFRS and Hantaviruses; 1994 May 1-June 3; Helsinki, Finland. Helsinki: Haartman Institute, University of Helsinki, 1994; 69.
  28. McKenna  P, van der Groen  G, Hoofd  G, Beelaert  G, Leirs  H, Verhagen  R. Eradication of hantavirus infection among laboratory rats by application of caesarian section and a foster mother technique. J Infect. 1992;25:181–90. DOIPubMedGoogle Scholar
  29. Heneberg  D, Vuksic  L, Morelj  M, Lepes  I, Djordjevic  Z, Mikes  M, Epidemic of hemorrhagic fever in certain workplaces in Fruska Gora. Zbornik radova VMA 1962:236-71.
  30. Antoniadis  A, Greekas  D, Rossi  CA, LeDuc  JW. Isolation of a hantavirus from a severely ill patient with hemorrhagic fever with renal syndrome in Greece. J Infect Dis. 1987;156:1010–3.PubMedGoogle Scholar
  31. Avsic-Zupanc  T, Poljak  M, Furlan  P, Kaps  R. Shu Yuan Xiao, LeDuc JW. Isolation of a strain of a hantaan virus from a fatal case of hemorrhagic fever with renal syndrome in Slovenia. Am J Trop Med Hyg. 1994;51:393–400.PubMedGoogle Scholar
  32. Gligic  A, Dimkovic  N, Xiao  SY, Buckle  GJ, Jovanovic  D, Velimirovic  D, Belgrade virus: a new hantavirus causing severe hemorrhagic fever with renal syndrome in Yugoslavia. J Infect Dis. 1992;166:113–20.PubMedGoogle Scholar
  33. Avsic-Zupanc  T, Xiao  S-Y, Stojanovic  R, Gligic  A, van der Groen  G, LeDuc  JW. Characterisation of Dobrava virus: a hantavirus from Slovenia, Yugoslavia. J Med Virol. 1992;38:132–7. DOIPubMedGoogle Scholar
  34. Antoniadis  A, Stylianakis  A, Papa  A, Alexiou-Daniel  S, Lampropoulos  A, Nichol  ST, Direct genetic detection of Dobrava virus in Greek and Albanian patients with hemorrhagic fever with renal syndrome. J Infect Dis. 1996;174:407–10.PubMedGoogle Scholar
  35. Hukic  M, Kurt  A, Torstensson  S, Lundkvist  A, Wiger  D, Niklasson  B. Haemorrhagic fever with renal syndrome in northeast Bosnia. Lancet. 1996;347:56–7. DOIPubMedGoogle Scholar
  36. Lundkvist  A, Hukic  M, Hörling  J, Gilljam  M, Nichol  S, Niklasson  B. Puumala and Dobrava viruses cause haemorrhagic fever with renal syndrome (HFRS) in Bosnia-Herzegovina: evidence of highly cross-neutralizing antibody responses in early patient sera. J Med Virol. In press.
  37. Clement  J, Mc Kenna  P, Avsic Zupanc  T, Skinner  CR. Rat-transmitted hantavirus disease in Sarajevo. Lancet. 1994;344:131. DOIPubMedGoogle Scholar
  38. Clement  J, Heyman  P, Colson  P, Groeneveld  PH. Spread of hantavirus infections in Europe. Lancet. 1996;347:771. DOIPubMedGoogle Scholar
  39. Plyusnin  A, Vapalahti  O, Lankinen  H, Lehvaslaiho  H, Apekina  N, Myasnikov  Y, Tula virus : a newly detected hantavirus carried by European common voles. J Virol. 1994;68:7833–9.PubMedGoogle Scholar
  40. Song  W, Torrez Martinez  N, Irwin  W, Harrison  FJ, Davis  R, Ascher  M, Isla Vista virus: a genetically novel hantavirus of the California vole Microtus californicus. J Gen Virol. 1995;76:3195–9. DOIPubMedGoogle Scholar
  41. Vapalahti  O, Lundkvist  A, Kukkonen  S, Cheng  Y, Giljam  M, Kaverna  M. Isolation and characterisation of Tula virus, a distinct serotype in the genus Hantavirus, family Bunyaviridae. J Gen Virol. In press.
  42. Plyusnin  A, Vapalahti  O, Lundkvist  A, Henttonen  H, Vaheri  A. Newly recognized hantavirus in Siberian lemmings. Lancet. 1996;347:1835. DOIPubMedGoogle Scholar
  43. Brummer Korvenkontio  M, Vaher  A, Hovi  T, von Bonsdoff  C, Vuorimies  J, Manni  T, Nephropathia epidemica: detection of antigen in bank voles and serologic diagnosis of human infection. J Infect Dis. 1980;141:131–4.PubMedGoogle Scholar
  44. Kariwa  H, Yoshizumi  S, Arikawa  J, Yoshimatsu  K, Takahashi  K, Takashima  I, Evidence for the existence of Puumula-related virus among Clethrio-nomys rufocanus in Hokkaido, Japan. Am J Trop Med Hyg. 1995;53:222–7.PubMedGoogle Scholar
  45. Lee  PW, Amyz  HL, Gajdusek  DC, Yanagihara  RT, Goldgaber  D, Gibbs  CJ. New haemorrhagic fever with renal syndrome-related virus in indigenous wild rodents in United States. Lancet. 1982;2:1405.
  46. Hörling  J, Chizhikov  V, Lundkvist  A, Jonsson  M, Ivanov  L, Dekonenko  A, Khabarovsk virus: a phylogenetically and serologically distinct hantavirus isolated from Microtus fortis trapped in far-east Russia. J Gen Virol. 1996;77:687–94. DOIPubMedGoogle Scholar

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