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Volume 30, Number 10—October 2024
Research

Evidence of Lineage 1 and 3 West Nile Virus in Person with Neuroinvasive Disease, Nebraska, USA, 2023

Emily Davis1, Jason Velez1, Jeff Hamik, Kelly Fitzpatrick, Jacki Haley, Jeremy Eschliman, Amanda Panella, J. Erin Staples, Amy Lambert, Matthew Donahue, Aaron C. Brault, and Holly R. HughesComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (E. Davis, J. Velez, K. Fitzpatrick, A. Panella, J.E. Staples, A. Lambert, A.C. Brault, H.R. Hughes); Nebraska Department of Health and Human Services, Lincoln, Nebraska, USA (J. Hamik, M. Donahue); Two Rivers Public Health Department, Kearney, Nebraska, USA (J. Haley, J. Eschliman)

Main Article

Figure 2

Consensus sequences for lineage 1 and lineage 3 WNV in serum and after Vp1 in samples from a patient with neuroinvasive disease and evidence of lineage 1 and 3 WNV infection, Nebraska, USA, 2023. Lineage 1 and lineage 3 WNV are distinct at the consensus level compared with Vp1 and historical strains. A, B) The consensus sequence of lineage 1 WNV in serum was compared with that of Vp1 (A), and those 2 sequences were then compared with the prototypical North American lineage 1 WNV strain, NY99 (B). C) Serum lineage 3 WNV consensus sequence was compared with the partial lineage 3 WNV sequences determined from Vp1 and CSF and historical lineage 3 WNV strains. C, capsid; CSF, cerebrospinal fluid; E, envelope; NS, nonstructural; prM, premembrane; Vp1, Vero passage 1; WNV, West Nile virus.

Figure 2. Consensus sequences for lineage 1 and lineage 3 WNV in serum and after Vp1 in samples from a patient with neuroinvasive disease and evidence of lineage 1 and 3 WNV infection, Nebraska, USA, 2023. Lineage 1 and lineage 3 WNV are distinct at the consensus level compared with Vp1 and historical strains. A, B) The consensus sequence of lineage 1 WNV in serum was compared with that of Vp1 (A), and those 2 sequences were then compared with the prototypical North American lineage 1 WNV strain, NY99 (B). C) Serum lineage 3 WNV consensus sequence was compared with the partial lineage 3 WNV sequences determined from Vp1 and CSF and historical lineage 3 WNV strains. C, capsid; CSF, cerebrospinal fluid; E, envelope; NS, nonstructural; prM, premembrane; Vp1, Vero passage 1; WNV, West Nile virus.

Main Article

1These first authors contributed equally to this article.

Page created: August 23, 2024
Page updated: September 23, 2024
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