Increase in Adult Patients with Varicella Zoster Virus–Related Central Nervous System Infections, Japan
Ayami Yoshikane, Hiroki Miura
, Sayuri Shima, Masaaki Matsunaga, Soichiro Ishimaru, Yuki Higashimoto, Yoshiki Kawamura, Kei Kozawa, Akiko Yoshikawa, Akihiro Ueda, Atsuhiko Ota, Hirohisa Watanabe, Tatsuro Mutoh, and Tetsushi Yoshikawa
Author affiliation: Fujita Health University School of Medicine, Toyoake, Japan (A. Yoshikane, H. Miura, S. Shima, M. Matsunaga, Y. Higashimoto, Y. Kawamura, K. Kozawa, A. Yoshikawa, A. Ueda, A. Ota, H. Watanabe, T. Mutoh, T. Yoshikawa); Kariya Toyota General Hospital, Kariya, Aichi, Japan (S. Ishimaru)
Main Article
Figure 1
Figure 1. Flowchart of virologic examinations of cerebrospinal fluid samples from 615 patients with suspected CNS infection increase in adult patients with VZV-related CNS infections, Japan. Real-time PCR was carried out to detect DNA of 7 human herpesviruses: HSV-1, HSV-2, VZV, CMV, EBV, HHV-6, and HHV-7. Statistical analyses of VZV DNA–positive patients were performed to determine the trends and clinical features of VZV-related CNS infections. CMV, cytomegalovirus; CNS, central nervous system; EBV, Epstein‐Barr virus; HHV, human herpesvirus; HSV, herpes simplex virus; VZV, varicella-zoster virus.
Main Article
Page created: October 04, 2024
Page updated: November 26, 2024
Page reviewed: November 26, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.