*Total number of intakes was 303,817. Intake screening is performed each time an adult in custody enters a new facility. Because persons in Federal Bureau of Prisons custody often move between facilities, an intake might have been completed for the same patient >1 time during this period. IV, intravenous; STI, sexually transmitted infection. †Federal Bureau of Prisons guidance identifies risk factors that might indicate an HIV-negative patient is at high risk for HIV infection upon release, such as vaginal or anal sex 6 months before or at any time during incarceration and HIV-positive partner, inconsistent use of condoms with partner(s) of unknown HIV status or at high risk for HIV, sex while using drugs, >1 sex partner, STI diagnosis 6 months before or at any time during incarceration, and shared needles for IV drug use 6 months before or at any time during incarceration or might engage in IV drug use upon release. ‡Includes syphilis, genital warts, chlamydia, gonorrhea, and herpes.