Tick-Borne Encephalitis, Lombardy, Italy
Alessandra Gaffuri, Davide Sassera
, Mattia Calzolari, Lucia Gibelli, Davide Lelli, Alessandra Tebaldi, Nadia Vicari, Alessandro Bianchi, Claudio Pigoli, Monica Cerioli, Luca Zandonà, Giorgio Varisco, Irene Bertoletti, and Paola Prati
Author affiliations: Bergamo Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Bergamo, Italy (A. Gaffuri, L. Zandonà, G. Varisco); University of Pavia, Italy, and The I.R.C.C.S. Policlinico San Matteo Foundation, Pavia, Italy (D. Sassera); Reggio Emilia Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Reggio Emilia, Italy (M. Calzolari); Milano Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Milano, Italy (L. Gibelli, C. Pigoli); Virology Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Brescia, Italy (D. Lelli); ASST Papa Giovanni XXIII Hospital, Bergamo, Italy (A. Tepaldi); Pavia Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Pavia, Italy (N. Vicari, P. Prati); Sondrio Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Sondrio, Italy (A. Bianchi, I. Bertoletti); Epidemiology Unit, Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna, Brescia (M. Cerioli).
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Figure 2
Figure 2. Histopathologic findings from the brain of a wild chamois with tick-borne encephalitis virus found in the Lombardy region of Italy in May 2023. A) Severe, chronic, nonpurulent meningoencephalitis characterized by perivascular lymphohistiocytic cuffs. Hematoxylin-eosin stain; original magnification ×20. B) Neuronal positivity for tick-borne encephalitis virus. Immunohistochemistry; original magnification ×20.
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