Volume 30, Number 3—March 2024
Research
Expansion of Neisseria meningitidis Serogroup C Clonal Complex 10217 during Meningitis Outbreak, Burkina Faso, 2019
Table 2
Characteristics | Suspected/probable cases† | Confirmed cases, n = 137 |
|||
---|---|---|---|---|---|
NmC | NmX | Streptococcus pneumoniae | Haemophilus influenzae | ||
Total no. cases |
164 |
103 |
13 |
16 |
5 |
Patient sex | |||||
F | 92 (56) | 45 (44) | 3 (23) | 5 (31) | 3 (60) |
M |
72 (44) |
58 (56) |
10 (77) |
11 (69) |
2 (40) |
Districts reporting cases | |||||
Diapaga | 87 (53) | 54 (52) | 6 (46) | 2 (13) | 2 (40) |
Sebba | 33 (20) | 30 (29) | 0 | 1 (6) | 0 |
Dori | 13 (8) | 2 (2) | 6 (46) | 2 (13) | 0 |
Bogandé | 14 (9) | 4 (4) | 0 | 4 (25) | 3 (60) |
Pama | 10 (6) | 5 (5) | 0 | 5 (31) | 0 |
Gayeri | 7 (4) | 8 (8) | 1 (8) | 2 (13) | 0 |
*Values are no. (%). A total of 301 cases were reported. NmC, Neisseria meningitidis serogroup C; NmX, Neisseria meningitidis serogroup X. †Includes 3 cases that met the definition of a probable case as previously described (18).
References
- Diallo AO, Kiemtoré T, Bicaba BW, Medah I, Tarbangdo TF, Sanou S, et al. Development and implementation of a cloud-based meningitis surveillance and specimen tracking system in Burkina Faso, 2018. J Infect Dis. 2019;220(Suppl 4):S198–205. DOIPubMedGoogle Scholar
- Patel JC, Soeters HM, Diallo AO, Bicaba BW, Kadadé G, Dembélé AY, et al.; MenAfriNet Consortium. MenAfriNet Consortium. MenAfriNet: a network supporting case-based meningitis surveillance and vaccine evaluation in the meningitis belt of Africa. J Infect Dis. 2019;220(Suppl 4):S148–54. DOIPubMedGoogle Scholar
- Greenwood B. Manson lecture. Meningococcal meningitis in Africa. Trans R Soc Trop Med Hyg. 1999;93:341–53. DOIPubMedGoogle Scholar
- Lingani C, Bergeron-Caron C, Stuart JM, Fernandez K, Djingarey MH, Ronveaux O, et al. Meningococcal meningitis surveillance in the African meningitis belt, 2004–2013. Clin Infect Dis. 2015;61(Suppl 5):S410–5. DOIPubMedGoogle Scholar
- Alderson MR, LaForce FM, Sobanjo-Ter Meulen A, Hwang A, Preziosi MP, Klugman KP. Eliminating meningococcal epidemics from the African meningitis belt: the case for advanced prevention and control using next-generation neningococcal conjugate vaccines. J Infect Dis. 2019;220(Suppl 4):S274–8. DOIPubMedGoogle Scholar
- Continuing risk of meningitis due to Neisseria meningitidis serogroup C in Africa: revised recommendations from a WHO expert consultation. Wkly Epidemiol Rec. 2017;92:612–7.PubMedGoogle Scholar
- Whittle HC, Evans-Jones G, Onyewotu I, Adjukiewicz A, Turunen U, Crockford J, et al. Group-C meningococcal meningitis in the northern savanna of Africa. Lancet. 1975;305:1377. DOIGoogle Scholar
- Broome CV, Rugh MA, Yada AA, Giat L, Giat H, Zeltner JM, et al. Epidemic group C meningococcal meningitis in Upper Volta, 1979. Bull World Health Organ. 1983;61:325–30.PubMedGoogle Scholar
- Koumare B, Achtman M, Cisse M, Wang JF, Giovanna M, Doumbia T. Etude antigénique de 337 souches de Neisseria meningitidis isolées au Mali. Intérêt épidémiologique et vaccinal. Med Mal Infect. 1995;25:1132–6. DOIGoogle Scholar
- Chow J, Uadiale K, Bestman A, Kamau C, Caugant DA, Shehu A, et al. Invasive meningococcal meningitis serogroup C outbreak in northwest Nigeria, 2015—third consecutive outbreak of a new strain. PLoS Curr. 2016;8:ecurrents.outbreaks.06d10b6b4e690917d8b0a04268906143.
- Funk A, Uadiale K, Kamau C, Caugant DA, Ango U, Greig J. Sequential outbreaks due to a new strain of Neisseria meningitidis serogroup C in northern Nigeria, 2013–14. PLoS Curr. 2014;6:ecurrents.outbreaks.b50c2aaf1032b3ccade0fca0b63ee518.
- Sidikou F, Zaneidou M, Alkassoum I, Schwartz S, Issaka B, Obama R, et al.; MenAfriNet consortium. Emergence of epidemic Neisseria meningitidis serogroup C in Niger, 2015: an analysis of national surveillance data. Lancet Infect Dis. 2016;16:1288–94. DOIPubMedGoogle Scholar
- Nnadi C, Oladejo J, Yennan S, Ogunleye A, Agbai C, Bakare L, et al. Large outbreak of Neisseria meningitidis serogroup C—Nigeria, December 2016–June 2017. MMWR Morb Mortal Wkly Rep. 2017;66:1352–6. DOIPubMedGoogle Scholar
- Kretz CB, Retchless AC, Sidikou F, Issaka B, Ousmane S, Schwartz S, et al.; Niger Response Team. Whole-genome characterization of epidemic Neisseria meningitidis serogroup C and resurgence of serogroup W, Niger, 2015. Emerg Infect Dis. 2016;22:1762–8. DOIPubMedGoogle Scholar
- Brynildsrud OB, Eldholm V, Bohlin J, Uadiale K, Obaro S, Caugant DA. Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa. Proc Natl Acad Sci U S A. 2018;115:5510–5. DOIPubMedGoogle Scholar
- World Health Organization. WHO and partners provide vaccines to control meningitis C in Nigeria. April 13, 2017 [cited 2022 Feb 10]. https://www.who.int/news/item/13-04-2017-who-and-partners-provide-vaccines-to-control-meningitis-c-in-nigeria
- Novak RT, Kambou JL, Diomandé FV, Tarbangdo TF, Ouédraogo-Traoré R, Sangaré L, et al. Serogroup A meningococcal conjugate vaccination in Burkina Faso: analysis of national surveillance data. Lancet Infect Dis. 2012;12:757–64. DOIPubMedGoogle Scholar
- World Health Organization. Standard operating procedures for surveillance of meningitis preparedness and response to epidemics in Africa. October 2018 [cited 2022 Feb 10]. https://apps.who.int/iris/bitstream/handle/10665/312141/9789290234241-eng.pdf
- Itsko M, Retchless AC, Joseph SJ, Norris Turner A, Bazan JA, Sadji AY, et al. Full molecular typing of Neisseria meningitidis directly from clinical specimens for outbreak investigation. J Clin Microbiol. 2020;58:e01780–20. DOIPubMedGoogle Scholar
- Dolan Thomas J, Hatcher CP, Satterfield DA, Theodore MJ, Bach MC, Linscott KB, et al. sodC-based real-time PCR for detection of Neisseria meningitidis. PLoS One. 2011;6:
e19361 . DOIPubMedGoogle Scholar - Katz S, Townsend-Payne K, Louth J, Lee-Jones L, Trotter C, Dan Dano I, et al.; MenAfriCar Consortium. Validation and use of a serum bactericidal antibody assay for Neisseria meningitidis serogroup X in a seroprevalence study in Niger, West Africa. Vaccine. 2022;40:6042–7. DOIPubMedGoogle Scholar
- World Health Organization. Control of epidemic meningococcal disease. WHO practical guidelines. 2nd edition. March 22, 1998 [cited 2022 Feb 10]. https://www.who.int/publications/i/item/control-of-epidemic-meningococcal-disease
- Teyssou R, Muros-Le Rouzic E. Meningitis epidemics in Africa: a brief overview. Vaccine. 2007;25(Suppl 1):A3–7. DOIPubMedGoogle Scholar
- Mueller JE, Gessner BD. A hypothetical explanatory model for meningococcal meningitis in the African meningitis belt. Int J Infect Dis. 2010;14:e553–9 . DOIPubMedGoogle Scholar
- World Health Organization Regional Office for Africa. Enhanced surveillance of meningitis in Africa, Republic of Congo, 2020–2023 [cited 2023 Aug 1]. https://app.powerbi.com/view?r=eyJrIjoiMzExZTUzZDAtMmQ5Ni00YjkxLWFmZmItODljOWZhOTMyM2Y3IiwidCI6ImY2MTBjMGI3LWJkMjQtNGIzOS04MTBiLTNkYzI4MGFmYjU5MCIsImMiOjh9
- Sultan B, Labadi K, Guégan JF, Janicot S. Climate drives the meningitis epidemics onset in west Africa. PLoS Med. 2005;2:
e6 . DOIPubMedGoogle Scholar - Molesworth AM, Cuevas LE, Connor SJ, Morse AP, Thomson MC. Environmental risk and meningitis epidemics in Africa. Emerg Infect Dis. 2003;9:1287–93. DOIPubMedGoogle Scholar
- Palmgren H. Meningococcal disease and climate. Glob Health Action. 2009;2:1. DOIPubMedGoogle Scholar
- Norwegian Refugee Council. Burkina Faso: almost 2 million people displaced amid worst food crisis in a decade. Sep 5, 2022 [cited 2022 Oct 5]. https://www.nrc.no/news/2022/september/burkina-faso-almost-2-million-people--now-displaced-amid-worst-food-crisis-in-a-decad
- World Health Organization. Assessing and improving the accuracy of target population estimates for immunization coverage. 2015 [cited 2022 Jun 1]. https://www.who.int/publications/m/item/assessing-and-improving-the-accuracy-of-target-population-estimates-for-immunization-coverage
- Nigeria Centre for Disease Control and Prevention. Cerebrospinal meningitis situation report, report 06, epidemiological week 23–26 (June 5–July 2, 2023) [cited 2023 Aug 1]. https://ncdc.gov.ng/diseases/sitreps/?cat=6&name=An%20Update%20of%20Meningitis%20Outbreak%20in%20Nigeria
1These senior authors contributed equally to this article.
Page created: December 31, 2023
Page updated: February 22, 2024
Page reviewed: February 22, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.