Volume 30, Number 9—September 2024
CME ACTIVITY - Research
Clinical Aspects and Disease Severity of Streptococcus dysgalactiae Subspecies equisimilis Bacteremia, Finland1
, Janne Aittoniemi, Reetta Huttunen, Tiina Luukkaala, and Sari Rantala
Table 2
Disease severity among 159 episodes of Streptococcus dysgalactiae subspecies equisimilis bacteremia during November 2015–November 2019, Finland*
| Characteristic | Total, n = 159 | Survivors, n = 150 | Nonsurvivors, n = 9 | p value |
|---|---|---|---|---|
| Admitted to intensive care unit |
11 (7) |
8 (5) |
3 (33) |
0.017 |
| Needed mechanical ventilation | 3 (2) | 2 (1) | 1 (11) | 0.161 |
| Needed continuous renal replacement therapy | 1 (1) | 1 (1) | 0 | NA |
| Needed hemodialysis | 1 (1) | 1 (1) | 0 | NA |
| Needed vasopressors |
15 (9) |
12 (8) |
3 (33) |
0.041 |
| Lowered level of consciousness† | 37 (23) | 31 (21) | 6 (67) | 0.005 |
| Unconscious |
7 (4) |
4 (3) |
3 (33) |
0.004 |
| Hypotension‡ | 36 (23) | 30 (20) | 6 (67) | 0.005 |
| Septic shock§ | 18 (11) | 13 (9) | 5 (56) | 0.001 |
| Disseminated intravascular coagulation¶ | 6 (4) | 5 (3) | 1 (11) | 0.299 |
| Multiorgan failure# |
12 (8) |
8 (5) |
4 (44) |
0.002 |
| Underwent surgical intervention | 38 (24) | 33 (22) | 5 (56) | 0.037 |
*Values are no. (%) except as indicated; p values compare survivors and nonsurvivors. NA, not applicable. †Lowered level of consciousness (unconscious or confusion) >1 time during the first 2 days after positive blood culture. ‡Systolic blood pressure <90 mm Hg >1 time during days 0–2 after positive blood culture. §Use of vasopressor and blood lactate level >2 mmol/L >1 time during days 0–2 after positive blood culture. ¶Platelet counts <100 × 109/L. #Observed >3 concomitant organ failures.
1Preliminary results from this study were presented at the European Congress of Clinical Microbiology and Infectious Diseases; April 27–30, 2024; Barcelona, Spain.