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Volume 31, Number 1—January 2025
CME ACTIVITY - Synopsis
Pneumococcal Septic Arthritis among Adults, France, 2010–2018
Farida Hamdad
, Nadim El Bayeh, Gabriel Auger, Olivia Peuchant, Frédéric Wallet, Raymond Ruimy, Florence Reibel, Christian Martin, Marie-Cécile Ploy, Frédéric Robin, Chrislène Laurens, Philippe Lanotte, Marie Kempf, Jennifer Tetu, Hélène Revillet, Isabelle Patry, Philippe Cailloux, Mélissa Azouaou, Emmanuelle Varon, Pierre Duhaut, Alain Lozniewski, and Vincent Cattoir
, Nadim El Bayeh, Gabriel Auger, Olivia Peuchant, Frédéric Wallet, Raymond Ruimy, Florence Reibel, Christian Martin, Marie-Cécile Ploy, Frédéric Robin, Chrislène Laurens, Philippe Lanotte, Marie Kempf, Jennifer Tetu, Hélène Revillet, Isabelle Patry, Philippe Cailloux, Mélissa Azouaou, Emmanuelle Varon, Pierre Duhaut, Alain Lozniewski, and Vincent Cattoir
Table 2
Clinical, treatment-related, and prognostic characteristics of patients with pneumococcal septic arthritis, France, 2010–2018*
| Characteristic or finding | Value |
|---|---|
| Demographic | |
| Sex | |
| F | 56/110 (50.9) |
| M | 54/110 (49.1) |
| Age, y, mean ± SD | 65.1 ± 14.6 |
| >65 y of age |
52/110 (47.3) |
| Clinical variables | |
| Pain | 30/110 (27.5) |
| Pain + fever + edema | 74/110 (67.9) |
| Native joint | 82/110 (74.6) |
| Prosthetic joint | 28/110 (25.4) |
| Single joint affected | 94/110 (85.5) |
| Multiple joints affected |
16/110 (14.5) |
| Joints affected | |
| Knee | 50/110 (45.5) |
| Hip | 25/110 (22.7) |
| Ankle | 15/110 (13.6) |
| Spondylodiscitis | 15/110 (13.6) |
| Wrist | 10/110 (9.1) |
| Shoulder | 8 /110 (7.3) |
| Sacroiliac joint | 4/110 (3.6) |
| Elbow | 1/110 (0.9) |
| Acromioclavicular joint | 1/110 (0.9) |
| Pubic symphysis |
1/110 (0.9) |
| Concomitant infections | |
| Bacteremia | 55/96 (57.3) |
| Respiratory infection | 29/102 (28.4) |
| Endocarditis | 5/102 (4.9) |
| Meningitis |
4/102 (3.9) |
| Main medical risk factor | |
| Hematologic malignancy | 12/83 (14.4) |
| Diabetes | 11/83 (13.2) |
| Alcoholism | 8/83 (9.6) |
| Active smoking | 8/83 (9.6) |
| Multiple myeloma | 6/83 (7.2) |
| Solid cancer | 6/83 (7.2) |
| Chronic kidney failure | 6/83 (7.2) |
| Splenectomy | 5/83 (6.0) |
| Heart disease | 4/83 (4.8) |
| Rheumatoid arthritis | 3/83 (3.6) |
| HIV |
3/83 (3.6) |
| Antimicrobial therapy, mean ± SD duration, d | |
| Duration of intravenous drug therapy | 19.1 ± 15.2 |
| Overall duration of antimicrobial therapy |
54.1 ± 54.3 |
| Surgery | |
| Joint drainage or lavage | 44/86 (51.2) |
| Arthrotomy | 13/86 (15.5) |
| Prothesis removal or replacement |
16/26 (61.5) |
| Outcome | |
| Sequelae | 9/82 (11) |
| Death | 8/85 (9.4) |
*Values are no. cases/total no. (%) unless otherwise indicated.
Page created: December 02, 2024
Page updated: December 19, 2024
Page reviewed: December 19, 2024
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