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Volume 31, Number 1—January 2025
Dispatch

Influenza A(H5N1) Virus Clade 2.3.2.1a in Traveler Returning to Australia from India, 2024

Yi-Mo Deng1, Michelle Wille1, Clyde Dapat, Ruopeng Xie, Olivia Lay, Heidi Peck, Andrew J. Daley, Vijaykrishna Dhanasakeran, and Ian G. BarrComments to Author 
Author affiliation: World Health Organization Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia (Y.-M. Deng, M. Wille, C. Dapat, O. Lay, H. Peck, I.G. Barr); The University of Melbourne, Melbourne (M. Wille, I.G. Barr); The University of Hong Kong, Hong Kong, China (R. Xie, V. Dhanasakeran); The Royal Children's and Royal Women's Hospitals, Parkville, Victoria, Australia (A.J. Daley)

Main Article

Figure 1

Evolutionary origins of isolate A/Victoria/149/2024(H5N1) (red circles and bold text) in study of influenza A(H5N1) virus clade 2.3.2.1a in traveler returning to Australia from India, 2024. A) Reassortant origins of A/Victoria/149/2024 based on analysis of each segment; detailed phylogenies for all segments are provided in Appendix Figure 1). B–D) Maximum-likelihood trees for HA (B), PB2 (C), and M (D) genes with a sample of BLAST-matched sequences (https://blast.ncbi.nlm.nih.gov). Bootstrap values >90% for key nodes are shown. Scale bars indicate number of nucleotide substitutions per site for each gene. HA, hemagglutinin; LPAI, low pathogenicity avian influenza; M, matrix protein; NP, nucleoprotein; NS, nonstructural; PA, polymerase acidic; PB1, polymerase basic 1; PB2, polymerase basic 2.

Figure 1. Evolutionary origins of isolate A/Victoria/149/2024(H5N1) (red circles and bold text) in study of influenza A(H5N1) virus clade 2.3.2.1a in traveler returning to Australia from India, 2024. A) Reassortant origins of A/Victoria/149/2024 based on analysis of each segment; detailed phylogenies for all segments are provided in Appendix Figure 1). B–D) Maximum-likelihood trees for HA (B), PB2 (C), and M (D) genes with a sample of BLAST-matched sequences (https://blast.ncbi.nlm.nih.gov). Bootstrap values >90% for key nodes are shown. Scale bars indicate number of nucleotide substitutions per site for each gene. HA, hemagglutinin; LPAI, low pathogenicity avian influenza; M, matrix protein; NP, nucleoprotein; NS, nonstructural; PA, polymerase acidic; PB1, polymerase basic 1; PB2, polymerase basic 2.

Main Article

1These authors contributed equally to this article.

Page created: November 20, 2024
Page updated: December 03, 2024
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