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Volume 31, Number 10—October 2025

Dispatch

Genomic Investigation of Disseminated Gonococcal Infections, Minnesota, USA, 2024

Daniel EvansComments to Author , Hannah Friedlander, Khalid Bo-Subait, Jefferson Dennis, John Kaiyalethe, Bradley Craft, Matthew Plumb, Bonnie Weber, Laura Bohnker-Voels, Kelly Pung, Alyssa Mondelli, Jacob Garfin, Jennifer Zipprich, Paula Snippes-Vagnone, Kathryn Como-Sabetti, and Ruth Lynfield
Author affiliation: Minnesota Department of Health, St. Paul, Minnesota, USA

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Figure 3

Phylodynamic inference of the emergence of Neisseria gonorrhoeae sequence type (ST) 11184 genomes that infected disseminated gonococcal infection cases, Minnesota, USA. The green bars denote the 90% CIs of the estimated time to most recent common ancestor (tMRCA) of a clade of 18 ST11184 genomes from Minnesota, rounded to the nearest month. We calculated tMRCAs by refining a maximum-likelihood, distance-scaled, core gene phylogenetic tree of publicly available ST11184 genomes into a time-scaled tree by using TreeTime v0.11.4 software (Appendix) (10). The dashed box denotes the period in which the tMRCA 90% CIs of all 16 iterations of time-scaled refinement overlapped. The red arrow denotes the time after the earliest collection of an isolate from a 2024 disseminated gonococcal infection case in Minnesota.

Figure 3. Phylodynamic inference of the emergence of Neisseria gonorrhoeae sequence type (ST) 11184 genomes that infected disseminated gonococcal infection cases, Minnesota, USA. The green bars denote the 90% CIs of the estimated time to most recent common ancestor (tMRCA) of a clade of 18 ST11184 genomes from Minnesota, rounded to the nearest month. We calculated tMRCAs by refining a maximum-likelihood, distance-scaled, core gene phylogenetic tree of publicly available ST11184 genomes into a time-scaled tree by using TreeTime v0.11.4 software (Appendix) (10). The dashed box denotes the period in which the tMRCA 90% CIs of all 16 iterations of time-scaled refinement overlapped. The red arrow denotes the time after the earliest collection of an isolate from a 2024 disseminated gonococcal infection case in Minnesota.

Main Article

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Page updated: September 25, 2025
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