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Volume 31, Number 11—November 2025
Dispatch
Neoehrlichia mikurensis in Ticks and Tick-Bitten Persons, Sweden and Finland, 2008–2009
Table 1
The prevalence of Neoehrlichia mikurensis determined in 1,644 Ixodes ricinus ticks collected from 1,425 humans who were bitten in Sweden or on the Åland Islands, Finland, during May 2008–November 2009
| Developmental stage of the tick | Total no. ticks analyzed | No. (%) N. mikurensis PCR-positive ticks* |
|---|---|---|
| Adult females | 392 | 5 (1.3) |
| Adult males | 7 | 0 |
| Nymphs | 1138 | 13 (1.1) |
| Larvae | 69 | 0 |
| Undetermined† | 38 | 0 |
| Total | 1644 | 18 (1.1) |
*PCR-positive tick was defined as a tick that tested positive for N. mikurensis in both the SYBR Green and TaqMan real-time PCR assays. †Tick developmental stage remains undetermined because of damages as previously described (7).
References
- Welinder-Olsson C, Kjellin E, Vaht K, Jacobsson S, Wennerås C. First case of human “Candidatus Neoehrlichia mikurensis” infection in a febrile patient with chronic lymphocytic leukemia. J Clin Microbiol. 2010;48:1956–9. DOIPubMedGoogle Scholar
- Portillo A, Santibáñez P, Palomar AM, Santibáñez S, Oteo JA. ‘Candidatus Neoehrlichia mikurensis’ in Europe. New Microbes New Infect. 2018;22:30–6. DOIPubMedGoogle Scholar
- Höper L, Skoog E, Stenson M, Grankvist A, Wass L, Olsen B, et al. Vasculitis due to Candidatus Neoehrlichia mikurensis: a cohort study of 40 Swedish patients. Clin Infect Dis. 2021;73:e2372–8. DOIPubMedGoogle Scholar
- Markowicz M, Schötta AM, Höss D, Kundi M, Schray C, Stockinger H, et al. Infections with tickborne pathogens after tick bite, Austria, 2015–2018. Emerg Infect Dis. 2021;27:1048–56. DOIPubMedGoogle Scholar
- Jahfari S, Hofhuis A, Fonville M, van der Giessen J, van Pelt W, Sprong H. Molecular detection of tick-borne pathogens in humans with tick bites and erythema migrans, in the Netherlands. PLoS Negl Trop Dis. 2016;10:
e0005042 . DOIPubMedGoogle Scholar - Wilhelmsson P, Fryland L, Lindblom P, Sjöwall J, Ahlm C, Berglund J, et al. A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the Åland Islands, Finland (2008-2009). Ticks Tick Borne Dis. 2016;7:71–9. DOIPubMedGoogle Scholar
- Wilhelmsson P, Lindblom P, Fryland L, Ernerudh J, Forsberg P, Lindgren PE. Prevalence, diversity, and load of Borrelia species in ticks that have fed on humans in regions of Sweden and Åland Islands, Finland with different Lyme borreliosis incidences. PLoS One. 2013;8:
e81433 . DOIPubMedGoogle Scholar - Wilhelmsson P, Lindblom P, Fryland L, Nyman D, Jaenson TG, Forsberg P, et al. Ixodes ricinus ticks removed from humans in Northern Europe: seasonal pattern of infestation, attachment sites and duration of feeding. Parasit Vectors. 2013;6:362. DOIPubMedGoogle Scholar
- Gray J, Stanek G, Kundi M, Kocianova E. Dimensions of engorging Ixodes ricinus as a measure of feeding duration. Int J Med Microbiol. 2005;295:567–72. DOIPubMedGoogle Scholar
- Labbé Sandelin L, Tolf C, Larsson S, Wilhelmsson P, Salaneck E, Jaenson TG, et al. Candidatus Neoehrlichia mikurensis in ticks from migrating birds in Sweden. PLoS One. 2015;10:
e0133250 . DOIPubMedGoogle Scholar - Grankvist A, Sandelin LL, Andersson J, Fryland L, Wilhelmsson P, Lindgren PE, et al. Infections with Candidatus Neoehrlichia mikurensis and cytokine responses in 2 persons bitten by ticks, Sweden. Emerg Infect Dis. 2015;21:1462–5. DOIPubMedGoogle Scholar
- Andersson M, Bartkova S, Lindestad O, Råberg L. Co-infection with ‘Candidatus Neoehrlichia Mikurensis’ and Borrelia afzelii in Ixodes ricinus ticks in southern Sweden. Vector Borne Zoonotic Dis. 2013;13:438–42. DOIPubMedGoogle Scholar
- Wass L, Grankvist A, Bell-Sakyi L, Bergström M, Ulfhammer E, Lingblom C, et al. Cultivation of the causative agent of human neoehrlichiosis from clinical isolates identifies vascular endothelium as a target of infection. Emerg Microbes Infect. 2019;8:413–25. DOIPubMedGoogle Scholar
- Grankvist A, Jaén-Luchoro D, Wass L, Sikora P, Wennerås C. Comparative genomics of clinical isolates of the emerging tick-borne pathogen Neoehrlichia mikurensis. Microorganisms. 2021;9:1488. DOIPubMedGoogle Scholar
- Jahfari S, Fonville M, Hengeveld P, Reusken C, Scholte EJ, Takken W, et al. Prevalence of Neoehrlichia mikurensis in ticks and rodents from North-west Europe. Parasit Vectors. 2012;5:74. DOIPubMedGoogle Scholar
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