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Volume 31, Supplement—April 2025
SUPPLEMENT ISSUE
Supplement

Integrating Genomic Data into Public Health Surveillance for Multidrug-Resistant Organisms, Washington, USA

Laura Marcela Torres1Comments to Author , Jared Johnson1, Audrey Valentine1, Audrey Brezak, Emily C. Schneider, Marisa D’Angeli, Jennifer Morgan, Claire Brostrom-Smith, Chi N. Hua, Michael Tran, Darren Lucas, Joenice Gonzalez De Leon, Drew MacKellar, Philip Dykema, Kelly J. Kauber, and Allison Black
Author affiliation: Washington State Department of Health, Shoreline, Washington, USA (L.M. Torres, J. Johnson, A. Valentine, A. Brezak, E.C. Schneider, M. D’Angeli, C.N. Hua, M. Tran, D. Lucas, J. Gonzalez De Leon, D. Mackellar, P. Dykema, K.J. Kauber, A. Black); Public Health Seattle and King County, Seattle, Washington, USA (J. Morgan, C. Brostrom-Smith)

Main Article

Table 2

Results of pilot study of genomic and epidemiologic surveillance of outbreaks of multidrug-resistant organism infections, Washington, USA*

Outbreak ID Pathogen No. health facilities No. cases, n = 36 No. isolates sequenced, n = 43 Epidemiologically linked only, n = 5 Epidemiologically and genomically linked, n = 32 Genomically linked only, n = 6
1 Pseudomonas aeruginosa 1 5 8† 0 6 2
2 Acinetobacter baumannii 1 5 6‡ 0 6 0
3 A. baumannii 1 6 6 0 6 0
4 A. baumannii 1 7 10† 3 6 1
5 A.baumannii 5 8 8 0 5 3
6 Klebsiella pneumoniae 1 5 5 2§ 3 0

*ID, identification. †One case had 3 isolates sequenced and 1 had 2 isolates sequenced. ‡One case had 2 isolates sequenced. §Sample 5 was placed into a separate genomic cluster due to relatively large pairwise genetic differences between this isolate and the remaining outbreak 6 isolates, as determined by PopPUNK (16).

Main Article

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1These first authors contributed equally to this article.

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