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Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 31, Number 2—February 2025
Research

Contribution of Limited Molecular Testing to Low Ehrlichiosis Diagnosis in High Incidence Area, North Carolina, USA

Alexis Siegler, Lauryn Ursery, Dana A. Giandomenico, Melissa B. Miller, Johanna S. Salzer, Alexis M. Barbarin, Carl Williams, and Ross M. BoyceComments to Author 
Author affiliation: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA (A. Siegler, L. Ursery, D.A. Giandomenico, M.B. Miller, R.M. Boyce); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.S. Salzer); North Carolina Department of Health and Human Services, Raleigh, North Carolina, USA (A.M. Barbarin, C. Williams)

Main Article

Table 1

Clinical symptoms among patients tested for tickborne disease at a visit within the University of North Carolina health system, March 24, 2022–April 14, 2023

Clinical symptoms No. (%) patients
Meets clinical criteria 273 (28.9)
Fever and headache 151 (55.3)
Fever and myalgia 152 (55.7)
Fever and anemia 92 (33.7)
Fever and thrombocytopenia* 65 (23.8)
Fever and hepatic transaminase elevation† 78 (28.6)
Fever and leukopenia‡ 42 (15.4)
Tick bite noticed in previous 2 weeks
77 (28.3)
Does not meet clinical criteria 672 (71.1)
Fever 14 (2.1)
Headache 145 (21.6)
Myalgia 168 (25)
Anemia 50 (7.3)
Thrombocytopenia 28 (4.2)
Hepatic transaminase elevation 47 (7)
Leukopenia 26 (3.9)
Bite noticed in 2-weeks prior 205 (30.5)
No symptoms or bite noticed 69 (10.3)

*Platelets <150,000/μL. †Aspartate aminotransferase >33 U/L or alanine aminotransferase >36 U/L. ‡leukocytes <4,000 cells/μL.

Main Article

Page created: January 13, 2025
Page updated: January 16, 2025
Page reviewed: January 16, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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