Volume 31, Number 4—April 2025
Synopsis
Alistipes Bacteremia in Older Patients with Digestive and Cancer Comorbidities, Japan, 2016–2023
Naoki Watanabe
, Tomohisa Watari, Naoto Hosokawa, and Yoshihito Otsuka
, Tomohisa Watari, Naoto Hosokawa, and Yoshihito Otsuka
Table 4
MIC values against antimicrobial drugs and antimicrobial resistance genes of Alistipes strains in a tertiary care center, Japan, 2016–2023*
| Strain name | PEN | SAM | AMC | TZP | CRO | FOX | IPM | CLI | MINO | MXF | MTZ | Resistance genes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Af KML 24003 | 0.06 | <0.5 | <0.25 | <4 | <1 | <1 | 1 | 1 | 4† | 0.5 | <0.5 | adeF, tet(Q) |
| Af KML 24010 | 0.06 | <0.5 | <0.25 | <4 | 4 | 4 | 0.5 | 1 | 2 | 0.5 | <0.5 | Not tested |
| Ao KML 24001 | >1 | 1 | 0.5 | <4 | 8 | 4 | 1 | <0.12 | 4† | >4 | <0.5 | adeF, tet(Q) |
| Ao KML 24005 | 0.5 | <0.5 | <0.25 | <4 | 2 | 2 | 2 | <0.12 | 8† | >4 | <0.5 | adeF, tet(Q) |
| Ao KML 24008 | >1 | 2 | 1 | <4 | >32 | 8 | 1 | 0.5 | 8† | >4 | <0.5 | adeF, tet(Q) |
| Ap KML 24002 | >1 | <0.5 | 0.5 | <4 | >32 | <1 | <0.25 | 2† | 4† | <0.25 | <0.5 | adeF, tet(Q), ermG |
| Ap KML 24006 | >1 | 1 | 2 | <4 | >32 | 4† | 1 | <0.12 | 8† | 1 | <0.5 | adeF, tet(Q), cfxA4 |
| Ap KML 24009 | <0.03 | <0.5 | <0.25 | <4 | <1 | <1 | 0.5 | <0.12 | 8† | 1 | <0.5 | adeF, tet(Q) |
| Ain KML 24004 | >1 | 8 | 8 | <4 | >32 | 32† | 1 | <0.12 | <0.25 | 1 | <0.5 | cfxA3 |
| Ain KML 24007 | >1 | 2 | 1 | <4 | 32 | 32 | 1 | <0.12 | <0.25 | 1 | <0.5 | Not detected |
| Total MIC50 | >1 | <0.5 | 0.5 | <4 | 8 | 4 | 1 | <0.12 | 4 | 1 | <0.5 | Not available |
| Total MIC90 | >1 | 2 | 2 | <4 | >32 | 32 | 1 | 1 | 8 | >4 | <0.5 | Not available |
*MIC values are μg/mL. Af, Alistipes finegoldii; Ain, Alistipes indistinctus; AMC, amoxicillin/clavulanic acid; Ao, Alistipes onderdonkii; Ap, Alistipes putredinis; CLI, clindamycin; CRO, ceftriaxone; FOX, cefoxitin; IPM, imipenem; MIC50, concentration required to inhibit 50% of strains; MIC90, concentration required to inhibit 90% of strains; MINO, minocycline; MTZ, metronidazole; MXF, moxifloxacin; PEN, penicillin; SAM, ampicillin/sulbactam; TZP, piperacillin/tazobactam. †Indicates the presence of a resistance gene for the drug within that class.
Page created: February 18, 2025
Page updated: March 24, 2025
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