Skip directly to page options Skip directly to A-Z link
Volume 31, Number 4—April 2025
Dispatch

Yaws Circulating in Nonhuman Primates, Uganda and Rwanda

Tony L. GoldbergComments to Author , Leah A. Owens, Julius Nziza, Richard Muvunyi, Jessica M. Rothman, Patrick Omeja, and Colin A. Chapman
Author affiliation: University of Wisconsin–Madison, Madison, Wisconsin, USA (T.L. Goldberg, L.A. Owens); Gorilla Doctors, Musanze, Rwanda (J. Nziza); Rwanda Development Board, Kigali, Rwanda (R. Muvunyi); Hunter College of City University of New York, New York, New York, USA (J.M. Rothman); New York Consortium in Evolutionary Primatology, New York (J.M. Rothman); Makerere University, Kampala, Uganda (P. Omeja); Vancouver Island University, Nanaimo, British Columbia, Canada (C.A. Chapman)

Main Article

Figure 2

Maximum-likelihood phylogenetic tree of Treponema pallidum genomes from study of yaws circulating in nonhuman primates, Uganda and Rwanda. The tree shows relationships among T. p. pertenue genomes (yellow) and is rooted with T. p. endemicum (blue) and T. p. pallidum (red) genomes. Bold text indicates sequence generated in this study from a Ugandan red colobus monkey. Taxon names include GenBank accession numbers, followed in parentheses by primate host, location of origin, and isolate name. The tree was inferred from a 1,072,667-position cleaned nucleotide alignment of 31 nonredundant sequences available in GenBank having genome coverage >97% and containing 4,716 variable positions. Black dots on nodes indicate bootstrap values of 100%; gray dots indicate 75%–99% bootstrap values based on 1,000 bootstrap replicates; values <75% are not shown. Scale bar indicates nucleotide substitutions per site. Ca, Cercocebus atys; Cp, Chlorocebus pygerythrus; Cs, Cercocebus sabaeus; Hs, Homo sapiens; Pa, Papio anubis; Ps, Piliocolobus tephrosceles; Pt, Pan troglodytes.

Figure 2. Maximum-likelihood phylogenetic tree of Treponema pallidum genomes from study of yaws circulating in nonhuman primates, Uganda and Rwanda. The tree shows relationships among T. p. pertenue genomes (yellow) and is rooted with T. p. endemicum (blue) and T. p. pallidum (red) genomes. Bold text indicates sequence generated in this study from a Ugandan red colobus monkey. Taxon names include GenBank accession numbers, followed in parentheses by primate host, location of origin, and isolate name. The tree was inferred from a 1,072,667-position cleaned nucleotide alignment of 31 nonredundant sequences available in GenBank having genome coverage >97% and containing 4,716 variable positions. Black dots on nodes indicate bootstrap values of 100%; gray dots indicate 75%–99% bootstrap values based on 1,000 bootstrap replicates; values <75% are not shown. Scale bar indicates nucleotide substitutions per site. Ca, Cercocebus atys; Cp, Chlorocebus pygerythrus; Cs, Cercocebus sabaeus; Hs, Homo sapiens; Pa, Papio anubis; Ps, Piliocolobus tephrosceles; Pt, Pan troglodytes.

Download

Main Article

Page created: February 21, 2025
Page updated: March 24, 2025
Page reviewed: March 24, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external