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Volume 4, Number 2—June 1998

Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae

Kerry Chant*, Raymond Chan†, Mitchell Smith*, Dominic E. Dwyer, Peter D. Kirkland§, and the NSW Expert Group
Author affiliations: *Public Health Unit, Sydney, Australia; †South Western Area Pathology Service, Sydney, Australia; ‡Institute of Clinical Pathology and Medical Research (ICPMR), Westmead, Australia; §Elizabeth Macarthur Agricultural Institute, Menangle, New South Wales, Australia; ¶Stephen Conaty, NSW Department of Health; Yvonne Cossart, University of Sydney; Gwendolyn Gilbert, ICPMR; Richard Jane, NSW Department of Agriculture; Robert Love, University of Sydney; Jeremy McAnulty, NSW Department of Health; William Rawlinson, University of New South Wales and SEALS Department, Prince of Wales Hospital, Sydney; and Evan Sergeant, NSW Department of Agriculture.

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Results of case investigations

Serologic testa Patient 1 Patient 2
Neutralizing antibody to new agent 128 512
Antibody to equine morbillivirus negative negative
CMV IgG positive positive
CMV IgM negative negative
EBV-VCA IgG positive positive
EBV-VCA IgM negative negative
EBV-EBNA IgG negative positive
Rubella IgG positive positive
Rubella IgM negative negative
Mycoplasma (CFT) < 4b 4b
Mycoplasma IgM negative negative
Adenovirus (CFT) 8b 8b
Enterovirus (CFT) 8b 8b
Influenza A (CFT) 32b 16b
Influenza B (CFT) 8b <4 (negative)
Leptospiral agglutinins negative negative
Brucella antibodies negative negative
Toxoplasma IgG positive positive
Toxoplasma IgM negative negative
Q Fever (phase 2 - CFT) negative negative
Measles IgG positive positive
Measles IgM negative negative
Mumps IgG positive positive
Mumps IgM negative negative
RSV (CFT) < 8b anticomplementary
Parainfluenza 1 (CFT) 32b < 16b
Parainfluenza 2 (CFT) 16b < 16b
Parainfluenza 3 (CFT) < 8b < 16b
HBsAg negative negative
anti-HBc negative negative
anti-HCV negative positivec
anti-HIV (Western Blot) negative negative
anti-HIV (EIA) negative negative

aCMV, cytomegalovirus; IgG, immunoglobulin G; EBV, Epstein-Barr virus; VCA, viral capsid antigen; EBNA, Epstein-Barr nuclear antigen; CFT, complement fixation test; RSV, respiratory syncytial virus; HBsAg, hepatitis B surface antigen; HBc, hepatitis B core; HCV, hepatitis C virus; EIA, enzyme immunoassay.
bNot significant.
cBy two screening enzyme immunoassays.

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Page created: December 15, 2010
Page updated: December 15, 2010
Page reviewed: December 15, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.