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Volume 7, Number 2—April 2001
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections
State of the Art

Emerging Mechanisms of Fluoroquinolone Resistance

David C. HooperComments to Author 
Author affiliation: Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

Main Article


Components of multidrug transport systems in selected bacterial pathogens

Efflux components
Membrane fusion protein
Outer membrane protein
Regulatory gene or mutation
Gram-negative bacteria
Pseudomonas aeruginosa MexB MexA OprM mexR
MexD MexC OprJ nfxB
MexF MexE OprN mexT
MexY MexX OprM mexZ
Escherichia coli AcrB AcrA TolC acrR, marA, robA, soxS
Gram-positive bacteria
Staphylococcus aureus NorA -- -- flqB promoter mutation, arlRS
Streptococcus pneumoniae PmrA -- -- ?

Main Article

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Page updated: April 17, 2012
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