Volume 7, Number 3—June 2001
Dispatch
Decreased Susceptibility to Ciprofloxacin in Salmonella enterica serotype Typhi, United Kingdom
E. John Threlfall
and Linda R. Ward
and Linda R. Ward
Table 1
Incidence of multidrug resistance and decreased susceptibility to ciprofloxacin in Salmonella enterica serotype Typhi, U.K., 1990-1999
| CPL strains also resistant to: |
||||||||
|---|---|---|---|---|---|---|---|---|
| Year | Strainsa | MDRB no. (%) | Decreased susceptibility to CPL no (/%) | C | A | Tm | Ct | Cf |
| 1990 | 248 | 50 (20) | 0 (0) | 0 | 0 | 0 | 0 | 0 |
| 1991 | 226 | 48 (21) | 2 (0.9) | 1 | 1 | 1 | 0 | 0 |
| 1992 | 204 | 49 (24) | 1 (0.5) | 0 | 0 | 0 | 0 | 0 |
| 1993 | 194 | 49 (25) | 1 (0.5) | 1 | 1 | 1 | 0 | 0 |
| 1994 | 259 | 94 (36) | 5 (2) | 5 | 5 | 5 | 0 | 0 |
| 1995 | 291 | 100 (34) | 8 (3) | 5 | 5 | 5 | 0 | 0 |
| 1996 | 210 | 52 (25) | 11 (7) | 7 | 7 | 7 | 0 | 0 |
| 1997 | 174 | 22 (13) | 9 (5) | 6 | 6 | 6 | 0 | 0 |
| 1998 | 151 | 34 (23) | 32 (21) | 19 | 19 | 19 | 0 | 0 |
| 1999 | 179 | 47 (26) | 42 (23) | 25 | 25 | 25 | 0 | 0 |
aStrains referred to Laboratory of Enteric Pathogens.
bMDR = multidrug resistant (to chloramphenicol, ampicillin, and trimethoprim). Resistance symbols: C, chloramphenicol; A, ampicillin; Tm, trimethoprim; CPL, ciprofloxacin (MIC 0.25-1.0 mg/L); Ct, ceftriaxone; Cf, cefotaxime. Percentages of total isolates in parentheses.
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