Volume 8, Number 11—November 2002
Genomewide Pattern of Synonymous Nucleotide Substitution in Two Complete Genomes of Mycobacterium tuberculosis
|Accession nos.||Protein function||pS||pN|
|Probable differential deletion|
|NP_216319, NP_336310||PE repeat family||0.0115||0.0094|
|NP_215965, NP_335949||PE repeat family||0.0448||0.0185|
|Possible horizontal gene transfer|
|NP_215835, NP_335809||adenylate cyclase||0.0229||0.0068|
|NP_216564, NP_336573||polyketide synthase||0.0093||0.0036|
|Mean ± S.E.||0.0286 ± 0.0050||0.0085 ± 0.0019a|
aPaired sample t-test of the hypothesis that pS = pN , p<0.01. The quantities pS and pN are the proportion of nucleotide difference per synonymous site and per nonsynonymous site, respectively.
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