Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States
Identifying the Sources of Tuberculosis in Young Children: A Multistate Investigation
Sumi J. Sun*
, Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
, Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
Table 5
Comparison of drug-susceptibility and genotyping results for isolates of suspected patient pairsa with any drug resistance
| Source-patient isolate | Secondary patient isolate (children <5 years of age) | Drug-susceptibility comparison (patient pairs) | Genotype comparison (patient pairs) |
|---|---|---|---|
| Isoniazid | Isoniazid, streptomycin | Discordant | Concordant |
| Isoniazid, rifampin | Isoniazid, rifampin, ethambutol, streptomycin | Discordant | Concordant |
| Streptomycin | Pan-susceptible | Discordant | Concordant |
| Streptomycin | Streptomycin | Concordant | Concordant |
| Isoniazid, streptomycin | Isoniazid, streptomycin | Concordant | Concordant |
| Pan-susceptibleb | Ethionamide | Undeterminedc | Concordant |
| Not done | Streptomycin | Undetermined | Undetermined |
aTuberculosis patients <5 years of age and their suspected source patients.
bIsolate from source patient was not tested for ethionamide resistance.
cUndetermined, results unknown for one or both patients.
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