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Volume 8, Number 11—November 2002
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Identifying the Sources of Tuberculosis in Young Children: A Multistate Investigation

Sumi J. Sun*Comments to Author , Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
Author affiliations: *California Department of Health Services, Berkeley, California, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

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Table 5

Comparison of drug-susceptibility and genotyping results for isolates of suspected patient pairsa with any drug resistance

Source-patient isolate Secondary patient isolate
(children <5 years of age) Drug-susceptibility comparison
(patient pairs) Genotype
(patient pairs)
Isoniazid Isoniazid, streptomycin Discordant Concordant
Isoniazid, rifampin Isoniazid, rifampin, ethambutol, streptomycin Discordant Concordant
Streptomycin Pan-susceptible Discordant Concordant
Streptomycin Streptomycin Concordant Concordant
Isoniazid, streptomycin Isoniazid, streptomycin Concordant Concordant
Pan-susceptibleb Ethionamide Undeterminedc Concordant
Not done Streptomycin Undetermined Undetermined

aTuberculosis patients <5 years of age and their suspected source patients.
bIsolate from source patient was not tested for ethionamide resistance.
cUndetermined, results unknown for one or both patients.

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