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Volume 8, Number 2—February 2002

Lack of Evidence for Human-to-Human Transmission of Avian Influenza A (H9N2) Viruses in Hong Kong, China 19991

Timothy M. Uyeki*Comments to Author , Yu-Hoi Chong†, Jacqueline M. Katz*, Wilina Lim†, Yuk-Yin Ho†, Sophia S. Wang*, Thomas H.F. Tsang*, Winnie Wan-Yee Au†, Shuk-Chi Chan†, Thomas Rowe*, Jean Hu-Primmer*, Jensa C. Bell*, William W. Thompson*, Carolyn Buxton Bridges*, Nancy J. Cox*, Kwok-Hang Mak†, and Keiji Fukuda*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Department of Health, Hong Kong Special Administrative Region of China;

Main Article

Table 1

Clinical characteristics of two children infected with influenza A (H9N2) viruses, Hong Kong, 1999a

Patient characteristics History, symptoms, signs on admission Treatment received Laboratory studies Clinical course Outcome
13-month-old girl; possible failure to thrive; no recent travel Fever 39.5°C (1 day), poor appetite, vomiting, inflamed oropharynx Cefuroxime
Pseudoephedrine -
Triprolidine (No antiviral medications) CRPb 0.12 (mg/dL) (normal ≤0.8 mg/dL); WBC 2.22 x 109;
AST 66 IU/L;
CXR normal; U/A normal;
NP aspirate for influenza A EIA: pos NP aspirate for
viral culture: pos for influenza A (H9N2), adenovirus
type 3 Uneventful
No fever at
Duration of
hospitalization March 5-7, 1999 Recovered, no
4-year-old girl,
mild eczema, asthma, no recent travel Fever 38.9°C (1 day), malaise, sore throat,
headache, vomiting, abdominal pain, diarrhea
inflamed oropharynx Cefuroxime
(No antiviral
medications) CRP 0.25 (mg/dL); (normal ≤0.8 mg/dL); WBC 12.5 x 109
(82%N, 10%L, 7%M); CXR: normal; blood culture neg; stool culture neg; U/A normal; NP aspirate for
influenza A EIA pos; NP aspirate for viral culture pos for influenza A
(H9N2) Persistent fever, no fever at
Duration of
hospitalization March 1-8, 1999 Recovered, no

aSource: Epidemiologic investigation by the Hong Kong Department of Health and review of medical records.
bCRP = C-reactive protein; WBC = leukocytes; AST = aspartate aminotransferase; CXR = chest X-ray; U/A = urinalysis; NP = nasopharyngeal; EIA = enzyme immunoassay

Main Article

1Presented in part at the International Conference on Emerging Infectious Diseases 2000, Atlanta, Georgia, July 2000 (Poster #55), Session 7, July 16-19, 2000.

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Page updated: July 14, 2010
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