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Volume 8, Number 4—April 2002

Andes Virus and First Case Report of Bermejo Virus Causing Fatal Pulmonary Syndrome

Paula Padula*Comments to Author , Marcelo González Della Valle*, María Garcia Alai*, Pedro Cortada†, Mario Villagra‡, and Alberto Gianella§
Author affiliations: *Instituto Nacional de Enfermedades Infecciosas, Buenos Aires, Argentina; †Hospital San Vicente de Paul Orán, Salta, Argentina; ‡Centro Nacional de Enfermedades Tropicales, Santa Cruz, Bolivia; §Ministerio de Salud, La Paz, Bolivia.;

Main Article


Nucleotide and amino acid sequencea divergence comparisons between the 2 Bolivian patients and other hantavirus pulmonary syndrome (HPS)-related viruses of 2 fragments of the M segmentb, and 1 fragment of the S segmentc

Patient 1 Patient 2 ANDV Nort (Argentina) Bermejo virus (Argentina) RIOM (Bolivia) HTN007 (Peru) LN (Paraguay)
N G1 G2 N G1 G2 N G1 G2 N G1 G2 N G1 G2 N G1 G2 N G1 G2
Patient 1 5,9 19,8 NAd 1,4 3,3 3,1 NA 19,8 15,5 12,8 NA NA 14,2 NA NA 15,6 24,3 17,7
Patient 2 0 8,6 NA 6,2 21 NA NA 0 NA 14,2 NA NA 14,9 NA NA 17,3 29,2 NA
ANDV Nort (Argentina) 0 1,2 1,3 0 7,4 NA NA 21 14,2 13,2 NA NA 14,2 NA NA 16,6 23,1 17,7
Bermejo virus (Argentina) NA 8,6 2,7 NA 0 NA NA 7,4 1,3 NA NA NA NA NA NA NA 29,2 19
RIOM (Bolivia) 11,5 NA NA 11,5 NA NA 11,5 NA NA NA NA NA 5,5 NA NA 9 NA NA
HTN007 (Peru) 11,5 NA NA 11,5 NA NA 11,5 NA NA NA NA NA 2,1 NA NA 11,1 NA NA
LN (Paraguay) 12,5 14,8 8 12,5 17,3 NA 12,5 13,6 6,7 NA 17,3 5,3 2,1 NA NA 4,2 NA NA

aGenBank accesion numbers for the nucleotide sequences are: Patient 1 N:AF442561 G1:AF442559
G2:AF442560; Patient 2 N:AF442563 G1:AF442562; values above dashes are nucleotide sequence divergence and those below dashes are amino acid sequence divergence. The comparison analysis was performed using NALIGN and PALIGN programs from PCGENE 6.8 software from Intelligenetics Inc. (Mountain View CA).
bM segment G1 (nt 1735 to 1977); M segment G2 (nt 2718 to 2943).
cS segment N (nt 48 to 336)
dNA= not available

Main Article

Page created: July 15, 2010
Page updated: July 15, 2010
Page reviewed: July 15, 2010
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