Volume 8, Number 5—May 2002
Research
Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Children: Implications for the Use of Heptavalent Pnemococcal Conjugate Vaccine
Paola Marchisio*, Susanna Esposito*, Gian Carlo Schito†, Anna Marchese†, Roberta Cavagna*, Nicola Principi*
, and the Hercules Project Collaborative Group
, and the Hercules Project Collaborative Group
Table 2
Recovery of Streptococcus pneumoniae in the nasopharynx by age, 13 Italian cities, April 15–June 15, 2000a
| Age group (% of total/age group) | ||||
|---|---|---|---|---|
| Carriers | <2 yrs | 2-5 yrs | >5 yrs | Total |
| Total/age group | 420 | 1,389 | 990 | 2,799 |
| Total carriers | 26 (6.2) | 132 (9.5) | 84 (8.5) | 242 (8.6) |
| Carriers of invasive strains | 20 (74.1) | 106 (81.5) | 61 (71.2) | 187 (77.3) |
| Carriers of strains covered by the heptavalent vaccine | 19 (73.1)a | 91 (68.9)b | 43 (51.2)ab | 153 (63.2) |
aCarriers <2 yrs vs. carriers >5 yrs: p=0.040.
bCarriers 2-5 yrs vs. carriers >5 yrs: p=0.0008.
1The Hercules Project Collaborative Group includes: F. Schettini, D. De Mattia (Bari, Italy); G. P. Salvioli, G. Faldella (Bologna, Italy); G. Caramia, E. Ruffini (Ancona, Italy); E. Reali (Cinisello Balsamo, Italy); R. Longhi (Como, Italy); G. Bona (Novara, Italy); A. Guarino, F. Albano (Napoli, Italy); R. Malvicini (Fidenza, Italy); L. Ziino (Palermo, Italy); I. Barberi, T. Corona (Messina, Italy); P. Pusceddu (Cagliari, Italy); T. Meloni (Sassari, Italy); G. Saggese, and M. Migliaccio (Pisa, Italy).
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