Volume 9, Number 10—October 2003
Dispatch
Flying Squirrel–associated Typhus, United States
Table
Characteristic |
Case no. | |||
---|---|---|---|---|
I |
IIb |
III |
IV |
|
Sex |
Male |
Female |
Male |
Male |
Age (y) |
54 |
54 |
44 |
57 |
State of residence |
Massachusetts |
North Carolina |
West Virginia |
Georgia |
Mo of onset |
February 1998 |
September 1999 |
January 2002 |
March 2002 |
Flying squirrel contact |
Y |
Y |
Y |
Y |
Serologic titer (no. d from onset) |
||||
IgG Rickettsia prowazekii |
4,096 (10) |
nd |
128 (53) |
8,192 (7) |
8,192 (13) |
||||
32,768 (38) |
8,192 (23) |
|||
IgG R. typhi |
nd |
nd |
<32 (53) |
4,096 (7) |
4,096 (13) |
||||
4,096 (23) |
||||
IgM R. prowazekii |
nd |
2,048 (18) |
1,024 (53) |
nd |
IgM R. typhi |
nd |
512 (18) |
1,024 (53) |
nd |
Symptoms |
||||
Max fever (°C) |
nr |
40°C |
38°C |
40°C |
Chills |
Y |
nr |
Y |
Y |
Headache |
Y |
Y |
Y |
Y |
Rash (type, location) | nr | Y (macular, trunk) | N | Yc |
aIg, immunoglobulin; Y, yes; N, no; nd, not done; nr, not recorded.
bRecurrent illness, first episode January 1999, flying squirrel contact, rash at that time. Other symptoms associated with both episodes. Serologic titer from second episode.
cRash herpetic, not directly attributable to R. prowazekii infection but commonly seen in context of classic louse-borne epidemic typhus (8).
References
- Perine PL, Chandler BP, Krause DK, McCardle P, Awoke S, Habte-Gabr E, A clinico-epidemiological study of epidemic typhus in Africa. Clin Infect Dis. 1992;14:1149–58.PubMedGoogle Scholar
- Epidemic typhus associated with flying squirrels—United States. MMWR Morb Mortal Wkly Rep. 1982;31:555–6.PubMedGoogle Scholar
- Agger WA, Songsiridej V. Epidemic typhus acquired in Wisconsin. Wis Med J. 1985;84:27–30.PubMedGoogle Scholar
- Duma RJ, Sonenshine DE, Bozeman FM, Veazey JM Jr, Elisberg BL, Chadwick DP, Epidemic typhus in the United States associated with flying squirrels. JAMA. 1981;245:2318–23. DOIPubMedGoogle Scholar
- Bozeman FM, Masiello SA, Williams MS, Elisberg BL. Epidemic typhus rickettsiae isolated from flying squirrels. Nature. 1975;255:545–7. DOIPubMedGoogle Scholar
- McDade JE, Shepard CC, Redus MA, Newhouse VF, Smith JD. Evidence of Rickettsia prowazekii infections in the United States. Am J Trop Med Hyg. 1980;29:277–84.PubMedGoogle Scholar
- Strong RP, Shattuck GC, Sellards AW, Zinnser H, Hopkins JG. Typhus fever with particular reference to the Serbian epidemic. Cambridge (MA): American Red Cross at the Harvard University Press; 1920.
- Bozeman FM, Sonenshine DE, Williams MS, Chadwick DP, Lauer DM, Elisberg BL. Experimental infection of ectoparasitic arthropods with Rickettsia prowazekii (GvF-16 strain) and transmission to flying squirrels. Am J Trop Med Hyg. 1981;30:253–63.PubMedGoogle Scholar
- Lauer DM, Sonenshine DE. Bionomics of the squirrel flea, Orchopeas howarde (Siphonaptera: Ceratophyllidae), in laboratory and field colonies of the southern flying squirrel, Glaucomys volans, using radiolabeling techniques. J Med Entomol. 1978;15:1–10.
- Massung RF, Davis LE, Slater K, McKechnie DB, Puerzer M. Epidemic typhus meningitis in the southwestern United States. Clin Infect Dis. 2001;32:979–82. DOIPubMedGoogle Scholar
- Kaplan JE, McDade JE, Newhouse VF. Suspected Rocky Mountain spotted fever in the winter—epidemic typhus? N Engl J Med. 1981;305:1648. DOIPubMedGoogle Scholar
- Huys J, Kayhigi J, Freyens P, Berghe GV. Single-dose treatment of epidemic typhus with doxycyline. Chemotherapy. 1973;18:314–7. DOIPubMedGoogle Scholar
- Ormsbee R, Peacock M, Philip R, Casper E, Plorde J, Gabre-Kidan T, Serologic diagnosis of epidemic typhus fever. Am J Epidemiol. 1977;105:261–71.PubMedGoogle Scholar
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