Volume 9, Number 12—December 2003
Commentary
Influenza Pandemic Preparedness
Table
Issue | Bioterrorist event | Pandemic influenza | |
---|---|---|---|
Likelihood |
High |
High |
|
Warning |
None to days |
Days to months |
|
Occurrence |
Focal or multifocal |
Nationwide |
|
Transmission/duration of exposure |
Point source; limited; person-to-person |
Person-to-person, 6–8 wks |
|
Casualties |
Hundreds to thousands |
Hundreds of thousands to millions |
|
First responders susceptible? |
Yes |
Yes |
|
Disaster medical team support/response |
Yes |
No (too widespread) |
|
Main site for preparedness, response, recovery, and mitigation |
State and local areas |
State and local areas |
|
Essential preparedness components |
|||
Surveillance |
Yes |
Yes |
|
Law enforcement intelligence |
Yes |
No |
|
Investigation |
Yes |
Yes |
|
Research |
Yes |
Yes |
|
Liability programs |
Yes |
Yes |
|
Communication systems |
Yes |
Yes |
|
Medical triage and treatment plans |
Yes |
Yes |
|
Vaccine supply issues |
Yes (for most likely threats) |
Yes |
|
Drug supply issues |
Yes |
Yes |
|
Training/tabletop exercises |
Yes |
Yes |
|
Maintenance of essential community services |
Yes |
Yes |
|
Essential response components |
|||
Rapid deployment teams |
Yes |
No |
|
Effective communications/media relations strategy |
Yes |
Yes |
|
Vaccine delivery |
Yes (for some) |
Yes |
|
Drug delivery |
Yes (for most) |
Yes |
|
Hospital/public health coordination |
Yes |
Yes |
|
Global assistance |
Possibly |
Yes |
|
Medical care |
Yes |
Yes |
|
Mental health support |
Yes |
Yes |
|
Mortuary services |
Yes |
Yes |
|
Supplies and equipment |
Yes |
Yes |
|
Essential mitigation components |
|||
Enhanced surveillance |
Yes |
Yes |
|
Enhanced law enforcement intelligence |
Yes |
No |
|
Vaccine stockpile |
Yes (selected agents) |
Prototype vaccines only |
|
Drug stockpile |
Yes |
Yes |
|
Pre-event vaccination | Vaccination of selected groupsc | Vaccination of groups at medical high risk with pneumococcal vaccined |
aDuring a catastrophic infectious disease event, such as an influenza pandemic, there may be critical shortages of vaccines and drugs. Thus, clinics set up to administer vaccines and distribute antimicrobial drugs may require the services of a range of personnel whose fields of expertise are nonclinical. Examples of additional personnel that may be needed include law enforcement, translators, social workers, psychologists, and legal experts.
bSource: Adapted from: National Vaccine Program Office. Pandemic influenza: a planning guide for state and local officials (Draft 2.1). Atlanta: Centers for Disease Control and Prevention; 2000.
cAt the time of writing, the smallpox vaccination program was just beginning. For other bioterrorist agents for which vaccines are available (e.g., anthrax), limited supplies and concerns about safety profiles have, up to this point, effectively prevented the widespread use of these vaccines.
dIt may eventually be possible to vaccinate high-priority groups and the general population with a yet-to-be-developed “common epitope” vaccine, which might provide for a broader spectrum of protection against a variety of influenza A subtypes.
1A complete copy of each questionnaire and a complete set of the results are available from the corresponding author.