Volume 9, Number 6—June 2003
Research
Human Metapneumovirus Infections in Hospitalized Children1
Guy Boivin*†
, Gaston De Serres†‡, Stéphanie Côté*†, Rodica Gilca†‡, Yacine Abed*†, Louis Rochette†‡, Michel G. Bergeron*†, and Pierre Déry*†
, Gaston De Serres†‡, Stéphanie Côté*†, Rodica Gilca†‡, Yacine Abed*†, Louis Rochette†‡, Michel G. Bergeron*†, and Pierre Déry*†
Table 1
Type of laboratory confirmation by type of infection
| Laboratory test | HMPVa |
HRSV |
Influenza A |
Adenovirus |
PIV 2 |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No. tests | Positive (%) | No. tests | Positive (%) | No. tests | Positive (%) | No. tests | Positive (%) | Tests done | Positive (%) | ||
| PCR |
208 |
12 (5.8) |
208 |
106 (51.0) |
208 |
45 (21.6) |
NA |
NA |
NA |
NA |
|
| Culture |
145 |
2 (1.4 |
145 |
37 (25.5) |
145 |
10 (6.9) |
145 |
6 (4.1) |
145 |
1 (0.7%) |
|
| Antigen detection |
NA |
NA |
204 |
94 (46.1) |
172 |
19 (11.0) |
81 |
1 (1.2) |
76 |
1 (1.3%) |
|
| Total (+) in at least one test |
12 (5.8%) |
118 (56.7) |
49 (23.6) |
6 (4.1) |
2 (1.3%) |
||||||
| Delay between onset of symptoms and NPA, days; mean/median | 6.3/5.0 | 5.2/4.0 | 8.7/5.0 | 6.0/6.5 | 3.0/3.0 | ||||||
aHMPV, human metapneumovirus; HRSV, human respiratory syncytial virus; PIV, parainfluenza virus; NPA, nasopharyngeal aspirate; PCR, polymerase chain reaction; NA, not applicable.
1This study was presented in part at the 42nd International Conference on Antimicrobial Agents and Chemotherapy, September 27, 2002, San Diego, California.
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