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Volume 10, Number 7—July 2004
Research

Rapid Assessment Tool for Haemophilus influenzae type b Disease in Developing Countries1

Daniel R. Feikin*Comments to Author , Christopher B. Nelson†, James P. Watt*‡, Ezzeddine Mohsni§, Jay D. Wenger†, and Orin S. Levine*‡
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †World Health Organization, Geneva, Switzerland; ‡Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; §World Health Organization, Cairo, Egypt

Main Article

Table 1

Results of Haemophilus influenzae type b (Hib) rapid assessment tool in 11 developing countries

Country % culture-confirmeda Meningitis incidence rate method (MIR)
 Ratio meningitis cases U5MR:MIR
Hib meningitis rateb Hib meningitis ratec Cases/deathsd Cases/deathse
Ghana
 na
 0
 72f
 2,030/609
 10,148/2,030
 2.7
Uganda
 50
 44
 59
 2,533/633
 12,663/759
 1.1
Egypt
 50
 1
 23
 1,795/682
 8,977/539
 3.7
Iran
 67
 5
 7
 599/12
 2,994/180
 3.3
Jordan
 43
 6
 14
 107/5
 534/27
 2.9
Morocco
 44
 6
 23
 689/34
 3,443/172
 –
Oman
 43g
 27
 41
 112/11
 560/34
 0.43
Yemen
 NA
 0
 23h
 790/245
 3,950/897
 3.9
Kyrgyzstan
 33
 15
 20
 101/12
 505/51
 1.2
Uzbekistan
 NA
 0
 4j
 103/12
 515/52
 5.4
Bhutan 42 6 15 16/5 80/8 3.4

aMeningitis caused by Hib.
bUnadjusted meningitis incidence rate is the number of culture-confirmed Hib meningitis cases per 100,000 children <5 years of age in the study site without making any of the adjustments accounted for in the rapid assessment tool (see Methods).
cAdjusted meningitis incidence rate is the number of Hib meningitis cases per 100,000 children <5 years of age in the study site, as determined by the rapid assessment tool (see Methods).
dNational Hib meningitis.
eNational Hib pneumonia.
gBased on Gram stain of coccobacilli.
hBased on literature review and use of data from hospital.
iUnder-5 mortality rate excludes neonatal deaths.
jBased on use of data from Moscow study and rate of lumbar puncture in Uzbekistan.

Main Article

1Some of the content of this manuscript has previously been presented in a document on the Web site of the World Health Organization (http://www.who.int/vaccines-documents/DocsPDF01/www625.pdf).

Page created: January 27, 2011
Page updated: January 27, 2011
Page reviewed: January 27, 2011
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