Volume 15, Number 4—April 2009
Research
Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children
Table 2
Comparison of Streptococcus pneumoniae ST-2722 (Legacy strain) with the closest types that have 6 of the same alleles as ST-2722*
| ST | Serotypes | Allele profile of housekeeping genes† |
No. resistant/ total strains | Countries of isolation | Sources | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| aroE | gdh | gki | recP | spi | xpt | ddl | |||||
| 156 | 9V/14/11A/ 15C/19F | 7 | 11 | 10 | 1 | 6 | 8 | 1 | 38/59 | BR, CA, CZ, DK, FR, DE, HU, IL, IT, LB, NL, PL, SE, PT, QA, ES, UK, UY | Nasopharynx, cerebrospinal fluid, blood, pleural, sputum, ear |
| 1556 | 14 | 7 | 11 | 10 | 12 | 6 | 8 | 1 | 1/1 | DE | Blood |
| 1697 | 9V | 7 | 11 | 10 | 77 | 6 | 8 | 1 | 1 | UK | NA |
| 2684 | 11A | 7 | 11 | 10 | 10 | 6 | 8 | 1 | 1/1 | FR | Nasopharynx |
| 334 | 9 | 7 | 11 | 10 | 16 | 6 | 8 | 1 | 1/1 | NO | Blood |
| 1893 | 14 | 7 | 11 | 10 | 4 | 6 | 8 | 1 | 1 | NO | NA |
| 2616 | 14 | 7 | 11 | 10 | 2 | 6 | 8 | 1 | 1 | ES | Nasopharynx |
| 1227 | 14 | 7 | 11 | 10 | 29 | 6 | 8 | 1 | 1/1 | SE | Nasopharynx |
| 2128 | 9 | 7 | 11 | 10 | 5 | 6 | 8 | 1 | 1/1 | UK | Blood |
| 2722 | 19A | 7 | 11 | 10 | 15 | 6 | 8 | 1 | 1 | US | Ear |
*Types reported in the multilocus sequence typing database (http://spneumoniae.mlst.net). ST, sequence type; BR, Brazil; CA, Canada; CZ, Czech Republic; DE, Germany; DK, Denmark; FR, France; HU, Hungary; IL, Israel; IT, Italy; LB, Lebanon; NL, Netherlands; NO, Norway; PL, Poland; SE, Sweden; PT, Portugal; QA, Qatar; ES, Spain; UK, United Kingdom; UY, Uruguay; US, United States; NA, not available.
†aroE (shikimate dehydrogenase), gdh (glucose-6-phosphate dehydrogenase), gki (glucose kinase), recP (transketolase), spi (signal peptidase I), xpt (xanthine phosphoribosyltransferase), and ddl (D-alanine-D-alanine ligase).