Volume 15, Number 4—April 2009
Dispatch
Enterovirus 71 Maternal Antibodies in Infants, Taiwan
Shu-Ting Luo, Pai-Shan Chiang, An-Shine Chao, Guan-Yuan Liou, Reyin Lin, Tzou-Yien Lin, and Min-Shi Lee
Table 2
Biological half-life of maternal enterovirus 71 neutralizing antibodies in 154 seropositive neonates, determined by cross-sectional and longitudinal analyses, Taiwan*
| Antibody titers at 6 mo of age | No. | GMT at birth (SD†) | GMT at 6 mo | Cross-sectional mean half-life‡ | Longitudinal mean half-life§ |
|---|---|---|---|---|---|
| Detectable | 3 | 203 | 8 | 39 | 42 |
| Undetectable | 151 | 21 | 2 | 53 | 60 |
| Total | 154 | 22 (0.91) | 2 | 53 | 60 |
*GMT, geometric mean titer.
†After natural logarithm transformation.
‡Calculated on the basis of the GMT at birth and 6 months of age. For comparison, half-life is reported in days, assuming that1 month is equal to 30 days.
§Calculated on the basis of paired antibody titers in each individual.
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