Volume 15, Number 9—September 2009
Research
Clinical and Epidemiologic Characteristics of 3 Early Cases of Influenza A Pandemic (H1N1) 2009 Virus Infection, People’s Republic of China, 2009
, and for the National Influenza A Pandemic (H1N1) 2009 Clinical Investigation Group
Table 2
Clinical characteristics of 3 patients infected with influenza A pandemic (H1N1) 2009 virus, People’s Republic of China, 2009*
| Characteristic | Patient 1 | Patient 2 | Patient 3 |
|---|---|---|---|
| Chronic illness | No | No | No |
| Influenza vaccine in last flu season | No | No | No |
| Highest temperature, °C | 38.8 | 39 | 39.4 |
| Sore throat | Yes | Yes | Yes |
| Cough | Yes | No | Yes |
| Rhinorrhea | Yes | No | Yes |
| Nasal congestion | Yes | No | No |
| Headache | Yes | Yes | Yes |
| Diarrhea | No | No | No |
| Other symptoms | No | Decreased appetite | Chest pain |
| Leukocyte count, per mm3 | 7,900 | 4,900 | 5,300 |
| Neutrophil count, per mm3 | 5,480 | 2,810 | 4,000 |
| Lymphocyte count, per mm3 | 1,540 | 1,580 | 1,000 |
| Platelet count, per mm3 | 166,000 | 208,000 | 254,000 |
| C-reactive protein, mg/L | 39 | Not done | 0.3 |
| Findings on chest radiograph | Normal | Normal | Normal |
| Oseltamivir treatment* | Yes | Yes | Yes |
| Duration of fever, d | 2 | 3 | 3 |
| Length of stay in hospital, d† | 8 | 8 | 8 |
| Outcome | Recovered | Recovered | Recovered |
*75 mg 2x/d for 5 d.
†During their stay in hospital, no patient needed oxygen or a ventilator. They were kept in hospitals for isolation and close observation because pandemic (H1N1) 2009 was an infectious disease new to physicians in China.
1These authors contributed equally to this article.
2The National Influenza A Pandemic (H1N1) 2009 Clinical Investigation Group: Wang Chen, Cao Bin, Cao Zhixin, Tong Zhaohui (Beijing Chaoyang Hospital, Capital Medical University); Li Xingwang, Zhang Ming, Guo Limin, Chen Zhihai (Beijing Ditan Hospital); Chen Hong (Chengdu Infectious Diseases Hospital); Chen Shijun, Gai Zhongtao (Jinan Infectious Diseases Hospital); Xu Xiaoyuan, Wan Hua, Zheng Bo, Wang Guangfa (Peking University, First Hospital); Jiang Nan (Sichuan Province People’s Hospital); Wu Hao (Beijing Youan Hospital, Capital Medical University); Gao Zhancheng (Peking University, People’s Hospital); Zhao Mingwu (Peking University, Third Hospital); Liang Zongan (Sichuang University Huaxi Medical College); Gao Dachuan (Jinan Chest Hospital); Shu Yuelong, Zhang Weidong, Zhang Yanping (Chinese Center for Disease Control and Prevention);. Deng Guohua (Peking Union Medical College Hospital); Ren Lili (Chinese Academy of Medical Sciences); Zhao Min (Military 302 Hospital, Beijing); Zhu Qingyu (Academy of Military Medical Sciences)