Volume 16, Number 4—April 2010
CME ACTIVITY - Research
Community-associated Methicillin-Resistant Staphylococcus aureus Strains in Pediatric Intensive Care Unit1
Aaron M. Milstone
, Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. Perl
, Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. Perl
Table 3
Characteristics of patients colonized with different MRSA strain types at the time of PICU admission, The Johns Hopkins Hospital, Baltimore, MD, USA, March 2007–May 2008*
| Characteristic | Patients colonized with CA-MRSA strain, n = 40 | Patients colonized with HA-MRSA strain, n = 26 | OR (95% CI)† |
|---|---|---|---|
| Demographic | |||
| Median age, y (IQR) | 3.8 (1.0–5.9) | 4.0 (1.0–9.5) | 0.98 (0.90–1.07) |
| Male sex | 22 (55) | 14 (54) | 1.05 (0.39–2.82) |
| Race | |||
| White | 15 (35) | 9 (38) | Referent |
| African American | 23 (58) | 13 (50) | 1.1 (0.36–3.10) |
| Other | 2 (5) | 4 (15) | 0.3 (0.05–1.98) |
| Clinical | |||
| Newly identified MRSA carrier | 32 (80) | 20 (77) | 1.2 (0.36–3.97) |
| Hospitalized in previous 12 mo | 20 (50) | 19 (73) | 0.37 (0.13–1.07) |
| ICU admission in previous 12 mo | 13 (33) | 26 (62) | 0.31 (0.11–0.84) |
| Length of stay in hospital before
PICU admission, median (range) | 0 (0–28) | 0 (0–14) | 1.02 (0.92–1.15) |
| Primary service | |||
| Medical | 24 (60) | 12 (46) | Referent |
| Surgical | 16 (40) | 14 (54) | 0.57 (0.21–1.55) |
| Admitted to PICU from inpatient unit | 6 (19) | 5 (15) | 0.74 (0.20–2.73) |
| Outcomes | |||
| PICU length of stay,‡ median (IQR) | 3 (1–7.5) | 3 (2–7) | 1.05 (0.79–1.40) |
| Hospital length of stay,‡ median (IQR) | 8 (4.5–28.5) | 8.5 (3–15) | 1.04 (0.97–2.04) |
*MRSA, methicillin-resistant Staphylococcus aureus; PICU, pediatric intensive care unit; CA-MRSA, community-associated MRSA; HA-MRSA, hospital-associated MRSA; OR, odds ratio; CI, confidence interval; IQR, interquartile range. Values reported as no. (%) unless otherwise specified.
†Obtained from univariate logistic regression analysis.
‡Data were log transformed before regression analysis to account for skewing.
1These data were presented in part at the Annual Scientific Meeting of the Society of Healthcare Epidemiology of America, Orlando, Florida, USA, April 2008.
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