Volume 6, Number 3—June 2000
Research
Genetic Variation in Pneumocystis carinii Isolates from Different Geographic Regions: Implications for Transmission
Charles B. Beard*
, Jane L. Carter*, Scott P. Keely†, Laurence Huang‡, Norman J. Pieniazek*, Iaci N.S. Moura*, Jacquelin M. Roberts*, Allen W. Hightower*, Michelle S. Bens*, Amanda R. Freeman*, Sherline Lee*, James R. Stringer†, Jeffrey S. Duchin*, Carlos Del Rio§, David Rimland§¶, Robert P. Baughman#, Deborah A. Levy*, Vance J. Dietz*, Paul Simon*, and Thomas R. Navin*
, Jane L. Carter*, Scott P. Keely†, Laurence Huang‡, Norman J. Pieniazek*, Iaci N.S. Moura*, Jacquelin M. Roberts*, Allen W. Hightower*, Michelle S. Bens*, Amanda R. Freeman*, Sherline Lee*, James R. Stringer†, Jeffrey S. Duchin*, Carlos Del Rio§, David Rimland§¶, Robert P. Baughman#, Deborah A. Levy*, Vance J. Dietz*, Paul Simon*, and Thomas R. Navin*
Table 2
Genotype analysis of Pneumocystis carinii isolates at the DHPS locus
| Genotype | Nucleotide (amino acid) position/identity | Frequency N=220 (%) |
|---|---|---|
| 1 | 165 (55)/A (Thr) | 68 (30.9) |
| 171 (57)/C (Pro) | ||
| 2 | 165 (55)/G (Ala) | 13 (5.9) |
| 171 (57)/C (Pro) | ||
| 3 | 165 (55)/A (Thr) | 5 (2.3) |
| 171 (57)/T (Ser) | ||
| 4 | 165 (55)/G (Ala) | 109 (49.5) |
| 171 (57)/T (Ser) | ||
| mixed | 25 (11.4) |
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