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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States

Identifying the Sources of Tuberculosis in Young Children: A Multistate Investigation

Sumi J. Sun*Comments to Author , Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
Author affiliations: *California Department of Health Services, Berkeley, California, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

Main Article

Table 3

Demographic, clinical, and risk characteristics of 53 source patients with tuberculosis (TB) identified from public health investigationsa

Source patient characteristics No. (%)
Age group, yrs
15–24 11 (21)
25–44 28 (53)
45–64 10 (19)
65+ 4 (8)
Female 24 (45)
Race or ethnicity
Black, non-Hispanic 22 (42)
Hispanic 24 (45)
Asian 5 (9)
Native American or Alaskan Native 2 (4)
Foreign-bornb 27 (51)
Bacteriologic results, sputum
Smear positive/culture positive 42 (79)
Smear positive/culture negative 1 (2)
Smear negative/culture positive 8 (15)
Smear not done/culture not done 2 (4)
Cavitary chest radiographc 33 (63)
Provider type
Health department 31 (58)
Private provider 11 (11)
Both 11 (11)
Directly observed therapyd 47 (71)
Previous diagnosis of TB 5 (9)
Drug-resistant isolatee 5 (9)

aThree source patients were identified as the source of infection for more than one culture-confirmed patient who was <5 years of age in the sentinel study population; two source patients transmitted to two children, and one transmitted to three children.
bCountry of origin was Mexico for 14 (26%) of the foreign-born patients.
cResults unknown for one patient.
dCompared to patients on self-administered therapy.
eDrug resistance on initial testing of isolate; resistance to at least one of the following: isoniazid, rifampin, ethambutol, pyrazinamide, streptomycin, and ethionamide. Testing results for one or more drugs could have been unknown or not done. Excludes one source patient for whom drug susceptibility testing was not done.

Main Article

Page created: July 19, 2010
Page updated: July 19, 2010
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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